2021 San Diego Padres
League	National League
Division	West
Ballpark	Petco Park
City	San Diego, California
Record	79–83 (.488)
Divisional place	3rd
Owners	Peter Seidler
General managers	A. J. Preller
Managers	Jayce Tingler
Television	Bally Sports San Diego (Don Orsillo, Mark Grant, Mike Pomeranz, Mark Sweeney, Jesse Agler) Bally Deportes San Diego (Spanish)
Radio	KWFN 97.3 FM (Jesse Agler, Tony Gwynn Jr., Mark Grant) XEMO 860 AM (Spanish) (Eduardo Ortega, Carlos Hernandez, Pedro Gutierrez)
← 2020 Seasons 2022 →

The 2021 San Diego Padres season was the 53rd season of the San Diego Padres franchise. The Padres played their home games at Petco Park as members of Major League Baseball's National League West. The Padres entered the 2021 season expecting to contend for the World Series, having made several major acquisitions in the offseason, and held a playoff position in the Wild Card standings from April to late August. The Padres struggled down the stretch after reaching a season high 66-49 record, going 13-34 the rest of the way. The Padres were eliminated from playoff contention on September 25, and finished the 2021 season with a very disappointing record of 79–83.

On April 9, 2021, newly acquired Joe Musgrove pitched a 3–0 no-hitter against the Texas Rangers, the first no-hitter in San Diego Padres history. The no-hitter also broke a streak of having gone 8,205 games without throwing one, a major league record.^[1]

Position	Player	2020 Team
SP	Joe Musgrove	Pittsburgh Pirates
SP	Yu Darvish	Chicago Cubs
CP	Mark Melancon	Atlanta Braves
SP	Blake Snell	Tampa Bay Rays
IF	Ha-seong Kim	Kiwoom Heroes (KBO)
C	Victor Caratini	Chicago Cubs
OF	Brian O'Grady	Tampa Bay Rays
RP	Nick Ramirez	Detroit Tigers
OF	Patrick Kivlehan	Toronto Blue Jays
RP	Nabil Crismatt	St. Louis Cardinals
OF	John Andreoli	Boston Red Sox
RP	Aaron Northcraft	Miami Marlins

Position	Player	2021 Team
SP	Zach Davies	Chicago Cubs
SP	Garrett Richards	Boston Red Sox
RP	Trevor Rosenthal	Oakland Athletics
1B	Mitch Moreland	Oakland Athletics
CP	Kirby Yates	Toronto Blue Jays
C	Francisco Mejia	Tampa Bay Rays
RP	Luis Perdomo	Milwaukee Brewers
SP	Joey Lucchesi	New York Mets
RP	David Bednar	Pittsburgh Pirates
IF	Greg Garcia	Detroit Tigers
RP	Luis Patiño	Tampa Bay Rays
C	Jason Castro	Houston Astros
OF	Abraham Almonte	Atlanta Braves

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NL West

Team	W	L	Pct.	GB	Home	Road
San Francisco Giants	107	55	.660	—	54‍–‍27	53‍–‍28
Los Angeles Dodgers	106	56	.654	1	58‍–‍23	48‍–‍33
San Diego Padres	79	83	.488	28	45‍–‍36	34‍–‍47
Colorado Rockies	74	87	.460	32½	48‍–‍33	26‍–‍54
Arizona Diamondbacks	52	110	.321	55	32‍–‍49	20‍–‍61

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Division Leaders

Team	W	L	Pct.
San Francisco Giants	107	55	.660
Milwaukee Brewers	95	67	.586
Atlanta Braves	88	73	.547

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Wild Card teams
(Top 2 teams qualify for postseason)

Team	W	L	Pct.	GB
Los Angeles Dodgers	106	56	.654	+16
St. Louis Cardinals	90	72	.556	—
Cincinnati Reds	83	79	.512	7
Philadelphia Phillies	82	80	.506	8
San Diego Padres	79	83	.488	11
New York Mets	77	85	.475	13
Colorado Rockies	74	87	.460	15½
Chicago Cubs	71	91	.438	19
Miami Marlins	67	95	.414	23
Washington Nationals	65	97	.401	25
Pittsburgh Pirates	61	101	.377	29
Arizona Diamondbacks	52	110	.321	38

2021 National League record v t e Source: MLB Standings Grid – 2021
Team	AZ	ATL	CHC	CIN	COL	LAD	MIA	MIL	NYM	PHI	PIT	SD	SF	STL	WSH	AL
Arizona	—	3–4	2–4	5–1	9–10	3–16	2–5	1–6	1–5	4–3	4–2	8–11	2–17	1–6	3–4	4–16
Arizona	—	3–4	2–4	5–1	9–10	3–16	2–5	1–6	1–5	4–3	4–2	8–11	2–17	1–6	3–4	4–16
Atlanta	4–3	—	5–2	4–3	2–4	2–4	11–8	3–3	10–9	10–9	4–3	4–2	3–3	6–1	14–5	6–14
Chicago	4–2	2–5	—	8–11	3–3	4–3	1–5	4–15	4–3	2–5	14–5	5–1	1–6	9–10	4–3	6–14
Cincinnati	1–5	3–4	11–8	—	5–2	3–3	5–2	9–10	3–3	4–2	13–6	1–6	1–6	10–9	5–2	9–11
Colorado	10–9	4–2	3–3	2–5	—	6–13	4–2	2–5	2–5	5–2	4–2	11–8	4–15	3–4	4–2	10–10
Los Angeles	16–3	4–2	3–4	3–3	13–6	—	3–4	4–3	6–1	4–2	6–0	12–7	9–10	4–3	7–0	12–8
Miami	5–2	8–11	5–1	2–5	2–4	4–3	—	3–3	9–10	10–9	2–5	3–4	3–4	0–6	8–11	3–17
Milwaukee	6–1	3–3	15–4	10–9	5–2	3–4	3–3	—	4–2	2–5	14–5	5–2	4–3	8–11	5–1	8–12
New York	5–1	9–10	3–4	3–3	5–2	1–6	10–9	2–4	—	9–10	3–4	4–3	1–5	2–5	11–8	9–11
Philadelphia	3–4	9–10	5–2	2–4	2–5	2–4	9–10	5–2	10–9	—	4–3	4–2	2–4	4–3	13–6	8–12
Pittsburgh	2–4	3–4	5–14	6–13	2–4	0–6	5–2	5–14	4–3	3–4	—	3–4	4–3	7–12	2–4	10–10
San Diego	11–8	2–4	1–5	6–1	8–11	7–12	4–3	2–5	3–4	2–4	4–3	—	8–11	3–3	4–3	14–6
San Francisco	17–2	3–3	6–1	6–1	15–4	10–9	4–3	3–4	5–1	4–2	3–4	11–8	—	2–4	5–2	13–7
St. Louis	6–1	1–6	10–9	9–10	4–3	3–4	6–0	11–8	5–2	3–4	12–7	3–3	4–2	—	2–4	11–9
Washington	4–3	5–14	3–4	2–5	2–4	0–7	11–8	1–5	8–11	6–13	4–2	3–4	2–5	4–2	—	10–10

Updated with the results of all games through October 3, 2021.

2021 game log: 79–83 (Home: 45–36; Away: 34–47)
April: 15–12 (Home: 6–8; Away: 9–4) # Date Opponent Score Win Loss Save Attendance Record Streak 1 April 1 Diamondbacks 8–7 Pagán (1–0) Young (0–1) Melancon (1) 10,350 1–0 W1 2 April 2 Diamondbacks 4–2 Pagán (2–0) Kelly (0–1) Melancon (2) 10,350 2–0 W2 3 April 3 Diamondbacks 7–0 Musgrove (1–0) Smith (0–1) Weathers (1) 10,350 3–0 W3 4 April 4 Diamondbacks 1–3 Widener (1–0) Paddack (0–1) Devenski (1) 10,350 3–1 L1 5 April 5 Giants 2–3 Baragar (1–0) Stammen (0–1) McGee (2) 10,350 3–2 L2 6 April 6 Giants 4–1 Kela (1–0) Wisler (0–1) Melancon (3) 10,350 4–2 W1 7 April 7 Giants 2–3 (10) Rogers (1–0) Hill (0–1) — 10,350 4–3 L1 8 April 9 @ Rangers 3–0 Musgrove (2–0) Arihara (0–1) — 27,575 5–3 W1 9 April 10 @ Rangers 7–4 Weathers (1–0) Benjamin (0–1) Melancon (4) 35,856 6–3 W2 10 April 11 @ Rangers 2–0 Stammen (1–1) Foltynewicz (0–2) Melancon (5) 26,723 7–3 W3 11 April 12 @ Pirates 6–2 Darvish (1–0) Oviedo (0–1) — 4,068 8–3 W4 12 April 13 @ Pirates 4–8 Stratton (1–0) Crismatt (0–1) — 4,814 8–4 L1 13 April 14 @ Pirates 1–5 Anderson (1–2) Musgrove (2–1) — 5,228 8–5 L2 14 April 15 @ Pirates 8–3 Paddack (1–1) Keller (1–2) Stammen (1) 4,023 9–5 W1 15 April 16 Dodgers 6–11 (12) Price (1–0) Hill (0–2) — 15,250 9–6 L1 16 April 17 Dodgers 0–2 Kershaw (3–1) Darvish (1–1) González (1) 15,250 9–7 L2 17 April 18 Dodgers 5–2 Kela (2–0) Alexander (0–1) Melancon (6) 15,250 10–7 W1 18 April 19 Brewers 1–3 Woodruff (1–0) Musgrove (2–2) Hader (2) 15,250 10–8 L1 19 April 20 Brewers 0–6 Burnes (2–1) Paddack (1–2) — 15,250 10–9 L2 20 April 21 Brewers 2–4 Suter (1–1) Kela (2–1) Hader (3) 15,250 10–10 L3 21 April 22 @ Dodgers 3–2 Crismatt (1–1) Treinen (1–1) Melancon (7) 15,167 11–10 W1 22 April 23 @ Dodgers 6–1 Darvish (2–1) Kershaw (3–2) — 15,222 12–10 W2 23 April 24 @ Dodgers 4–5 Bauer (3–0) Johnson (0–1) Jansen (5) 15,596 12–11 L1 24 April 25 @ Dodgers 8–7 (11) Hill (1–2) Cleavinger (0–1) Melancon (8) 15,316 13–11 W1 25 April 27 @ Diamondbacks 1–5 Kelly (2–2) Paddack (1–3) — 10,486 13–12 L1 26 April 28 @ Diamondbacks 12–3 Northcraft (1–0) Smith (1–1) — 9,495 14–12 W1 27 April 30 Giants 3–2 Darvish (3–1) Webb (1–2) Melancon (9) 15,250 15–12 W2
May: 19–9 (Home: 12–2; Away: 7–7) # Date Opponent Score Win Loss Save Attendance Record Streak 28 May 1 Giants 6–2 Snell (1–0) DeSclafani (2–1) — 15,250 16–12 W3 29 May 2 Giants 1–7 Gausman (2–0) Musgrove (2–3) — 15,250 16–13 L1 30 May 3 Pirates 2–0 Hill (2–2) Anderson (2–3) Melancon (10) 15,250 17–13 W1 31 May 4 Pirates 1–2 Keller (2–3) Weathers (1–1) Rodríguez (5) 15,250 17–14 L1 32 May 5 Pirates 4–2 Stammen (2–1) Underwood Jr. (1–1) Melancon (11) 15,250 18–14 W1 33 May 7 @ Giants 4–5 Doval (1–1) Kela (2–2) McGee (8) 9,219 18–15 L1 34 May 8 @ Giants 1–7 Gausman (3–0) Musgrove (2–4) — 9,764 18–16 L2 35 May 9 @ Giants 11–1 Weathers (2–1) Cueto (2–1) — 10,008 19–16 W1 — May 10 @ Rockies Postponed (rain, makeup May 12) 36 May 11 @ Rockies 8–1 Díaz (1–0) Senzatela (1–4) — 8,825 20–16 W2 37 May 12 (1) @ Rockies 5–3 (7) Pagán (3–0) Gray (4–3) Melancon (12) N/A 21–16 W3 38 May 12 (2) @ Rockies 2–3 (8) Almonte (1–1) Ramirez (0–1) — 11,968 21–17 L1 39 May 14 Cardinals 5–4 Musgrove (3–4) Oviedo (0–2) Melancon (13) 15,250 22–17 W1 40 May 15 Cardinals 13–3 Díaz (2–0) Wainwright (2–4) — 15,250 23–17 W2 41 May 16 Cardinals 5–3 Lamet (1–0) Kim (1–1) Melancon (14) 15,250 24–17 W3 42 May 17 Rockies 7–0 Darvish (4–1) Gray (4–4) — 15,250 25–17 W4 43 May 18 Rockies 2–1 (10) Johnson (1–1) Bard (1–3) — 15,250 26–17 W5 44 May 19 Rockies 3–0 Musgrove (4–4) Gonzalez (2–2) Melancon (15) 15,250 27–17 W6 45 May 21 Mariners 16–1 Paddack (2–3) Flexen (4–2) — 15,250 28–17 W7 46 May 22 Mariners 6–4 Stammen (3–1) Sheffield (3–4) Melancon (16) 15,250 29–17 W8 47 May 23 Mariners 9–2 Darvish (5–1) Misiewicz (2–3) — 15,250 30–17 W9 48 May 24 @ Brewers 3–5 Woodruff (3–2) Snell (1–1) Hader (11) 14,524 30–18 L1 49 May 25 @ Brewers 7–1 Hill (3–2) Burnes (2–4) — 13,566 31–18 W1 50 May 26 @ Brewers 2–1 (10) Adams (1–0) Suter (3–3) Melancon (17) 13,478 32–18 W2 51 May 27 @ Brewers 5–6 (10) Suter (4–3) Díaz (2–1) — 13,572 32–19 L1 52 May 28 @ Astros 10–3 (11) Melancon (1–0) Raley (2–3) — 32,045 33–19 W1 53 May 29 @ Astros 11–8 (12) Adams (2–0) Garza (0–1) Díaz (1) 31,323 34–19 W2 54 May 30 @ Astros 4–7 Greinke (5–2) Snell (1–2) — 29,019 34–20 L1 55 May 31 @ Cubs 2–7 Stewart (1–0) Paddack (2–4) — 24,824 34–21 L2
June: 15–12 (Home: 12–5; Away: 3–7) # Date Opponent Score Win Loss Save Attendance Record Streak 56 June 1 @ Cubs 3–4 Hendricks (6–4) Weathers (2–2) Kimbrel (13) 24,824 34–22 L2 57 June 2 @ Cubs 1–6 Alzolay (4–4) Johnson (1–2) — 24,824 34–23 L3 58 June 3 Mets 4–3 Darvish (6–1) Walker (4–2) Melancon (18) 15,250 35–23 W1 59 June 4 Mets 2–0 Snell (2–2) Lucchesi (1–4) Melancon (19) 15,250 36–23 W2 60 June 5 Mets 0–4 deGrom (5–2) Musgrove (4–5) — 15,250 36–24 L1 61 June 6 Mets 2–6 Stroman (5–4) Paddack (2–5) — 15,250 36–25 L2 62 June 7 Cubs 9–4 Weathers (3–2) Alzolay (4–5) — 15,250 37–25 W1 63 June 8 Cubs 1–7 Davies (3–3) Lamet (1–1) — 16,207 37–26 L1 64 June 9 Cubs 1–3 Brothers (2–0) Darvish (6–2) Kimbrel (15) 15,250 37–27 L2 65 June 11 @ Mets 2–3 deGrom (6–2) Snell (2–3) Díaz (11) 26,637 37–28 L3 66 June 12 @ Mets 1–4 Stroman (6–4) Musgrove (4–6) Díaz (12) 25,463 37–29 L4 67 June 13 @ Mets 7–3 Paddack (3–5) Familia (2–1) — 19,581 38–29 W1 68 June 14 @ Rockies 2–3 Gomber (6–5) Lamet (1–2) Bard (9) 23,027 38–30 L1 69 June 15 @ Rockies 4–8 Estévez (1–0) Hill (3–3) — 22,871 38–31 L2 70 June 16 @ Rockies 7–8 Estévez (2–0) Adams (2–1) — 18,798 38–32 L3 71 June 17 Reds 6–4 Johnson (2–2) Garrett (0–2) — 40,362 39–32 W1 72 June 18 Reds 8–2 Paddack (4–5) Santillan (0–1) — 33,456 40–32 W2 73 June 19 Reds 7–5 Crismatt (2–1) Hembree (1–2) Melancon (20) 38,765 41–32 W3 74 June 20 Reds 3–2 Lamet (2–2) Castillo (2–10) Melancon (21) 38,004 42–32 W4 75 June 21 Dodgers 6–2 Darvish (7–2) Urías (9–3) — 42,220 43–32 W5 76 June 22 Dodgers 3–2 Snell (3–3) Kershaw (8–7) Melancon (22) 42,667 44–32 W6 77 June 23 Dodgers 5–3 Hill (4–3) Treinen (1–3) Melancon (23) 43,691 45–32 W7 78 June 25 Diamondbacks 11–5 Ramirez (1–1) Martin (0–3) — 32,583 46–32 W8 79 June 26 Diamondbacks 1–10 Kelly (4–7) Lamet (2–3) — 40,557 46–33 L1 80 June 27 Diamondbacks 5–4 Hill (5–3) Peacock (2–6) Melancon (24) 34,905 47–33 W1 81 June 29 @ Reds 5–4 Pagán (4–0) Santillan (1–2) Melancon (25) 16,332 48–33 W2 82 June 30 @ Reds 7–5 (6) Musgrove (5–6) Gutiérrez (3–3) Hill (1) 12,084 49–33 W3
July: 11–14 (Home: 5–7; Away: 6–7) # Date Opponent Score Win Loss Save Attendance Record Streak 83 July 1 @ Reds 4–5 Warren (1–0) Melancon (1–1) — 16,620 49–34 L1 84 July 2 @ Phillies 3–4 (10) Suárez (4–2) Adams (2–2) — 22,653 49–35 L2 85 July 3 @ Phillies 2–4 Eflin (3–6) Darvish (7–3) Suárez (1) 25,053 49–36 L3 86 July 4 @ Phillies 11–1 Adams (3–2) Velasquez (3–3) — 25,592 50–36 W1 87 July 5 Nationals 5–7 Suero (1–2) Hill (5–4) Hand (19) 33,168 50–37 L1 88 July 6 Nationals 7–4 Weathers (4–2) Fedde (4–5) Melancon (26) 29,977 51–37 W1 89 July 7 Nationals 5–15 Corbin (6–7) Paddack (4–6) — 26,353 51–38 L1 90 July 8 Nationals 9–8 Melancon (2–1) Clay (0–2) — 29,434 52–38 W1 91 July 9 Rockies 4–2 Díaz (3–1) Freeland (1–3) Melancon (27) 34,953 53–38 W2 92 July 10 Rockies 0–3 Márquez (8–6) Musgrove (5–7) Bard (13) 42,351 53–39 L1 93 July 11 Rockies 1–3 Gray (6–6) Stammen (3–2) Bard (14) 38,235 53–40 L2 91st All-Star Game in Denver, CO Representing the Padres: Fernando Tatís Jr., Jake Cronenworth, Manny Machado, Yu Darvish, & Mark Melancon 94 July 16 @ Nationals 24–8 Paddack (5–6) Fedde (4–7) — 29,203 54–40 W1 95 July 17[a]/18 @ Nationals 10–4 Stammen (4–2) Corbin (6–8) — 33,232 55–40 W2 96 July 18 @ Nationals 7–8 Hand (5–2) Melancon (2–2) — 27,221 55–41 L1 — July 19 @ Braves Postponed (Rain, makeup July 21) 97 July 20 @ Braves 1–2 Toussaint (1–0) Darvish (7–4) Smith (19) 36,621 55–42 L2 98 July 21 (1) @ Braves 3–2 (7) Paddack (6–6) Muller (1–3) Melancon (28) 28,621 56–42 W1 — July 21 (2) @ Braves Suspended (Rain, Makeup: September 24) 99 July 22 @ Marlins 3–2 Snell (4–3) Holloway (2–3) Melancon (29) 10,977 57–42 W2 100 July 23 @ Marlins 5–2 Musgrove (6–7) Thompson (2–3) Melancon (30) 9,264 58–42 W3 101 July 24 @ Marlins 2–3 Garrett (1–1) Hill (5–5) García (15) 13,207 58–43 L1 102 July 25 @ Marlins 3–9 Bender (2–1) Darvish (7–5) — 12,765 58–44 L2 103 July 27 Athletics 7–4 Paddack (7–6) Kaprielian (5–4) Melancon (31) 40,162 59–44 W1 104 July 28 Athletics 4–10 Manaea (8–6) Snell (4–4) — 35,351 59–45 L1 105 July 29 Rockies 3–0 Musgrove (7–7) Freeland (1–6) Melancon (32) 31,884 60–45 W1 106 July 30 Rockies 4–9 Gray (7–6) Weathers (4–3) — 38,686 60–46 L1 107 July 31 Rockies 3–5 Márquez (9–8) Darvish (7–6) Bard (16) 44,144 60–47 L2
August: 11–15 (Home: 6–7; Away: 5–8) # Date Opponent Score Win Loss Save Attendance Record Streak 108 August 1 Rockies 8–1 Stammen (5–2) Gomber (8–6) — 36,247 61–47 W1 109 August 3 @ Athletics 8–1 Snell (5–4) Manaea (8–7) — 11,985 62–47 W2 110 August 4 @ Athletics 4–5 (10) Trivino (4–4) Hill (5–6) — 10,648 62–48 L1 111 August 6 Diamondbacks 5–8 Peacock (5–6) Weathers (4–4) Poppen (1) 34,038 62–49 L2 112 August 7 Diamondbacks 6–2 Pomeranz (1–0) de Geus (2–1) — 39,134 63–49 W1 113 August 8 Diamondbacks 2–0 Snell (6–4) Bumgarner (6–7) Melancon (33) 30,989 64–49 W2 114 August 9 Marlins 8–3 Musgrove (8–7) Thompson (2–5) — 26,841 65–49 W3 115 August 10 Marlins 6–5 Johnson (3–2) Bleier (2-2) Melancon (34) 32,060 66–49 W4 116 August 11 Marlins 0–7 Alcántara (7–10) Weathers (4–5) — 29,753 66–50 L1 117 August 12 @ Diamondbacks 3–12 Smith (4–8) Darvish (7–7) — 9,086 66–51 L2 118 August 13 @ Diamondbacks 2–3 Clippard (1–0) Stammen (5–3) — 12,866 66–52 L3 119 August 14 @ Diamondbacks 0–7 Gilbert (1–1) Musgrove (8–8) — 16,716 66–53 L4 120 August 15 @ Diamondbacks 8–2 Knehr (1–0) Gallen (1–7) — 17,722 67–53 W1 121 August 16 @ Rockies 5–6 Bard (6–5) Hudson (4–2) — 24,565 67–54 L1 122 August 17 @ Rockies 3–7 Márquez (11–9) Strahm (0–1) — 28,139 67–55 L2 123 August 18 @ Rockies 5–7 Bowden (2–2) Arrieta (5–12) Bard (20) 20,692 67–56 L3 124 August 20 Phillies 3–4 Neris (2–5) Snell (6–5) Kennedy (20) 40,927 67–57 L4 125 August 21 Phillies 4–3 (10) Melancon (3–2) Brogdon (5–3) — 43,383 68–57 W1 126 August 22 Phillies 4–7 Gibson (9–5) Weathers (4–6) — 38,548 68–58 L1 127 August 24 Dodgers 2–5 Urías (14–3) Johnson (3–3) Jansen (28) 41,676 68–59 L2 128 August 25 Dodgers 3–5 (16) Knebel (3–0) Camarena (0–1) Greene (1) 41,765 68–60 L3 129 August 26 Dodgers 0–4 Scherzer (12–4) Darvish (7–8) — 43,383 68–61 L4 130 August 27 @ Angels 5–0 Musgrove (9–8) Criswell (0–1) — 25,376 69–61 W1 131 August 28 @ Angels 2–10 Wantz (1–0) Weathers (4–7) — 36,176 69–62 L1 132 August 30 @ Diamondbacks 7–5 Stammen (6–3) Gilbert (1–2) Melancon (35) 8,482 70–62 W1 133 August 31 @ Diamondbacks 3–0 Snell (7–5) Gallen (2–8) Melancon (36) 10,818 71–62 W2
September: 7–19 (Home: 4–7; Away: 3–12) # Date Opponent Score Win Loss Save Attendance Record Streak 134 September 1 @ Diamondbacks 3–8 Weaver (3–3) Darvish (7–9) — 5,945 71–63 L1 135 September 3 Astros 3–6 Taylor (3–4) Pagán (4–1) Pressly (23) 37,033 71–64 L2 136 September 4 Astros 10–2 Musgrove (10–8) Valdez (9–5) — 35,338 72–64 W1 137 September 5 Astros 4–3 Melancon (4–2) Stanek (1–4) — 35,007 73–64 W2 138 September 7 Angels 0–4 Herget (2–1) Snell (7–6) — 34,405 73–65 L1 139 September 8 Angels 8–5 Darvish (8–9) Mayers (3–4) Melancon (37) 34,537 74–65 W1 140 September 10 @ Dodgers 0–3 Urías (17–3) Musgrove (10–9) Jansen (31) 48,403 74–66 L1 141 September 11 @ Dodgers 4–5 Buehler (14–3) Paddack (7–7) Jansen (32) 46,969 74–67 L2 142 September 12 @ Dodgers 0–8 Scherzer (14–4) Lamet (2–4) — 42,637 74–68 L3 143 September 13 @ Giants 1–9 Littell (3–0) Darvish (8–10) — 21,078 74–69 L4 144 September 14 @ Giants 1–6 DeSclafani (12–6) Arrieta (5–13) — 23,192 74–70 L5 145 September 15 @ Giants 9–6 Musgrove (11–9) Leone (3–4) — 21,212 75–70 W1 146 September 16 @ Giants 7–4 Crismatt (3–1) Gausman (14–6) — 23,379 76–70 W2 147 September 17 @ Cardinals 2–8 Mikolas (1–2) Velasquez (3–7) — 30,937 76–71 L1 148 September 18 @ Cardinals 2–3 Miller (1–0) Pagán (4–2) Gallegos (9) 40,626 76–72 L2 149 September 19 @ Cardinals 7–8 Reyes (9–8) Arrieta (5–14) Gallegos (10) 35,326 76–73 L3 150 September 21 Giants 5–6 Watson (6–4) Melancon (4–3) Rogers (13) 36,439 76–74 L4 151 September 22 Giants 6–8 Doval (4–1) Velasquez (3–8) — 38,189 76–75 L5 152 September 23 Giants 7–6 (10) Detwiler (3–1) Leone (3–5) — 31,049 77–75 W1 153 September 24 (1) @ Braves 6–5 (7) Hudson (5–1) Smith (3–6) Melancon (29) N/A 78–75 W2 154 September 24 (2) Braves 0–4 Fried (13–7) Knehr (1–1) — 33,265 78–76 L1 155 September 25 Braves 8–10 (10) Rodríguez (5–4) Hudson (5–3) Smith (34) 39,026 78–77 L2 156 September 26 Braves 3–4 Minter (3–6) Johnson (3–4) Smith (35) 41,294 78–78 L3 157 September 28 @ Dodgers 1–2 Buehler (15–4) Darvish (8–11) Treinen (7) 52,128 78–79 L4 158 September 29 @ Dodgers 9–11 Price (5–2) Pagán (4–3) Jansen (37) 45,366 78–80 L5 159 September 30 @ Dodgers 3–8 Knebel (4–0) Velasquez (3–9) — 52,550 78–81 L6
October: 1–2 (Home: 0–0; Away: 1–2) # Date Opponent Score Win Loss Save Attendance Record Streak 160 October 1 @ Giants 0–3 DeSclafani (13–7) Ávila (0–1) Doval (3) 33,975 78–82 L7 161 October 2 @ Giants 3–2 (10) Hill (6–6) Castro (1–1) Melancon (39) 40,760 79–82 W1 162 October 3 @ Giants 4–11 Webb (11–3) Knehr (1–2) — 36,901 79–83 L1
Legend:        = Win        = Loss        = Postponement Bold = Padres team member

July 25: Tucupita Marcano, Jack Suwinski, & Michell Miliano to the Pittsburgh Pirates in exchange for 2B Adam Frazier

July 30: Mason Thompson & Jordy Barley to the Washington Nationals in exchange for RP Daniel Hudson

July 30: Anderson Espinoza to the Chicago Cubs for OF Jake Marisnick

2021 San Diego Padres
Roster
Pitchers 54 Austin Adams 57 Dan Altavilla 64 Shaun Anderson 49 Jake Arrieta 60 Pedro Ávila 72 Daniel Camarena 74 Nabil Crismatt 11 Yu Darvish 45 Ross Detwiler 37 Miguel Díaz  8 Javy Guerra 25 Tim Hill 18 Daniel Hudson 36 Pierce Johnson 27 Keone Kela 73 Reiss Knehr 29 Dinelson Lamet 33 Mark Melancon 50 Adrián Morejón 44 Joe Musgrove 43 Aaron Northcraft 67 James Norwood 59 Chris Paddack 14 Emilio Pagán 15 Drew Pomeranz 47 Nick Ramirez  4 Blake Snell 34 Craig Stammen 55 Matt Strahm 71 Mason Thompson 38 Vince Velasquez 40 Ryan Weathers 45 Taylor Williams		Catchers 21 Luis Campusano 17 Víctor Caratini 26 Austin Nola 48 Webster Rivas Infielders 61 Iván Castillo  9 Jake Cronenworth 12 Adam Frazier 30 Eric Hosmer  7 Ha-seong Kim 13 Manny Machado 23 Fernando Tatís Jr.		Outfielders 22 John Andreoli  2 Trent Grisham 18 Patrick Kivlehan 16 Tucupita Marcano 16 Jake Marisnick  3 Jorge Mateo  5 Wil Myers 24 Brian O'Grady 28 Tommy Pham 10 Jurickson Profar		Manager 32 Jayce Tingler Coaches 20 Rod Barajas (catching/quality control) 22 Bobby Dickerson (bench/third base) 46 Damion Easley (hitting) 84 Ryan Flaherty (advance scout/development) 89 Brad Flanders (bullpen catcher) 53 Ben Fritz (interim pitching coach) 41 Wayne Kirby (first base) 38 Larry Rothschild (pitching) 56 Skip Schumaker (associate manager) 83 Peter Summerville (bullpen catcher/coaching assistant) 82 Keith Werman (development coordinator)

Note: G = Games played; AB = At bats; R = Runs; H = Hits; 2B = Doubles; 3B = Triples; HR = Home runs; RBI = Runs batted in; SB = Stolen bases; BB = Walks; AVG = Batting average; SLG = Slugging average

Player	G	AB	R	H	2B	3B	HR	RBI	SB	BB	AVG	SLG
Jake Cronenworth	152	567	94	151	33	7	21	71	4	55	.266	.460
Manny Machado	153	564	92	157	31	2	28	106	12	63	.278	.489
Eric Hosmer	151	509	53	137	28	0	12	65	5	48	.269	.395
Fernando Tatís Jr.	130	478	99	135	31	0	42	97	25	62	.282	.611
Tommy Pham	155	475	74	109	24	2	15	49	14	78	.229	.383
Trent Grisham	132	462	61	112	28	3	15	62	13	54	.242	.413
Wil Myers	146	442	56	113	24	2	17	63	8	54	.256	.434
Jurickson Profar	137	353	47	80	17	2	4	33	10	49	.227	.320
Victor Caratini	116	313	33	71	9	0	7	39	2	35	.227	.323
Ha-seong Kim	117	267	27	54	12	2	8	34	6	22	.202	.352
Adam Frazier	57	191	25	51	8	1	1	11	5	13	.267	.335
Austin Nola	56	173	15	47	12	0	2	29	0	14	.272	.376
Jorge Mateo	57	87	10	18	4	0	2	6	5	2	.207	.322
Webster Rivas	24	68	8	15	2	0	2	4	0	8	.221	.338
Brian O'Grady	32	51	8	8	3	0	2	9	0	8	.157	.333
Jake Marisnick	34	48	4	9	1	0	0	2	1	2	.188	.208
Tucupita Marcano	25	44	7	8	1	0	0	3	0	6	.182	.205
Luis Campusano	11	34	0	3	0	0	0	1	0	4	.088	.088
John Andreoli	7	6	2	1	1	0	0	0	0	1	.167	.333
Patrick Kivlehan	5	4	3	1	0	0	0	2	0	2	.250	.250
Iván Castillo	3	3	0	1	0	0	0	1	0	1	.333	.333
Pitcher Totals	162	248	11	24	4	0	2	8	0	5	.098	.139
Team Totals	162	5384	729	1305	273	21	180	695	110	586	.242	.401

Source:[1]

Note: W = Wins; L = Losses; ERA = Earned run average; G = Games pitched; GS = Games started; SV = Saves; IP = Innings pitched; H = Hits allowed; R = Runs allowed; ER = Earned runs allowed; BB = Walks allowed; SO = Strikeouts

Player	W	L	ERA	G	GS	SV	IP	H	R	ER	BB	SO
Joe Musgrove	11	9	3.18	32	31	0	181.1	142	68	64	54	203
Yu Darvish	8	11	4.22	30	30	0	166.1	138	81	78	44	199
Blake Snell	7	6	4.20	27	27	0	128.2	101	61	60	69	170
Chris Paddack	7	7	5.07	23	22	0	108.1	115	67	61	22	99
Ryan Weathers	4	7	5.32	30	18	1	94.2	101	57	56	30	72
Craig Stammen	6	3	3.06	67	4	1	88.1	79	31	30	13	83
Nabil Crismatt	3	1	3.76	45	0	0	81.1	87	40	34	24	71
Mark Melancon	4	3	2.23	64	0	39	64.2	54	21	16	25	59
Emilio Pagán	4	3	4.83	67	0	0	63.1	56	35	34	18	69
Tim Hill	6	6	3.62	78	0	1	59.2	51	34	24	23	56
Pierce Johnson	3	4	3.22	63	2	0	58.2	47	21	21	27	77
Austin Adams	3	2	4.10	65	0	0	52.2	28	28	24	35	76
Dinelson Lamet	2	4	4.40	22	9	0	47.0	48	24	23	22	57
Miguel Díaz	3	1	3.64	25	2	1	42.0	31	19	17	19	46
Reiss Knehr	1	2	4.97	12	5	0	29.0	23	16	16	20	20
Drew Pomeranz	1	0	1.75	27	0	0	25.2	19	6	5	10	30
Nick Ramirez	1	1	5.75	13	0	0	20.1	23	15	13	7	14
Daniel Hudson	1	2	5.21	23	0	0	19.0	17	13	11	9	27
Vince Velasquez	0	3	8.53	4	4	0	12.2	15	13	12	4	16
Jake Arrieta	0	3	10.95	4	4	0	12.1	18	16	15	5	9
Keone Kela	2	2	5.06	12	0	0	10.2	11	8	6	3	13
Daniel Camarena	0	1	9.64	6	0	0	9.1	16	12	10	3	7
Aaron Northcraft	1	0	2.25	5	0	0	8.0	5	2	2	8	5
Ross Detwiler	1	0	2.57	7	0	0	7.0	3	2	2	5	6
Matt Strahm	0	1	8.10	6	1	0	6.2	15	6	6	1	4
Taylor Williams	0	0	1.69	5	0	0	5.1	3	1	1	3	6
James Norwood	0	0	0.00	5	0	0	5.0	6	0	0	3	3
Adrián Morejón	0	0	3.86	2	2	0	4.2	5	2	2	2	3
Shaun Anderson	0	0	5.79	5	0	0	4.2	6	3	3	2	4
Pedro Ávila	0	1	2.25	1	1	0	4.0	4	2	1	3	5
Javy Guerra	0	0	4.91	4	0	0	3.2	4	2	2	2	3
Mason Thompson	0	0	3.00	4	0	0	3.0	4	1	1	1	2
Dan Altavilla	0	0	6.75	2	0	0	1.1	1	1	1	0	2
Jake Cronenworth	0	0	0.00	1	0	0	0.2	1	0	0	0	1
Team Totals	79	83	4.10	162	162	43	1430.0	1277	708	651	516	1517

Source:[2]

Level	Team	League	Manager	W	L	Position
Triple-A	El Paso Chihuahuas	Triple-A West	Edwin Rodríguez	46	74	5th
Double-A	San Antonio Missions	Double-A Central	Phillip Wellman	57	63	4th
High-A	Fort Wayne TinCaps	High-A Central	Anthony Contreras	54	66	6th
Low-A	Lake Elsinore Storm	Low-A West	Mike McCoy	55	65	3rd
Rookie	ACL Padres	Arizona Complex League	Vinny Lopez	26	32	4th
Rookie	DSL Padres	Dominican Summer League	Miguel Del Castillo	37	21	2nd

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