This was the first tournament after the NAIA consolidated its basketball membership back into a single division, eliminating the separate championships that existed for its Divisions I and II from 1992 to 2020.
Westmont defeated Thomas More in the championship game, 72–61, the Warriors' second NAIA national title.
After the merger of the two NAIA divisional tournaments back into a single event, the field of the combined event was set to forty-eight teams.
The tournament continued to utilize a simple single-elimination format. The first two preliminary rounds were played on regional campus sites while all subsequent rounds were played at the final tournament site in Sioux City.
