2021 Christus Health Pro Challenge
Date	25–31 October 2021
Edition	5th
Category	ITF Women's World Tennis Tour
Prize money	$80,000
Surface	Hard
Location	Tyler, Texas, United States
Champions
Singles
Misaki Doi
Doubles
Giuliana Olmos / Marcela Zacarías
← 2020 · Tyler Pro Challenge · 2022 →

The 2021 Christus Health Pro Challenge was a professional women's tennis tournament played on outdoor hard courts. It was the fifth edition of the tournament which was part of the 2021 ITF Women's World Tennis Tour. It took place in Tyler, Texas, United States between 25 and 31 October 2021.^[1]

Country	Player	Rank1	Seed
USA	Madison Brengle	78	1
USA	Claire Liu	88	2
BRA	Beatriz Haddad Maia	94	3
JPN	Misaki Doi	106	4
GBR	Harriet Dart	134	5
CHN	Wang Xiyu	140	6
USA	Caty McNally	141	7
POL	Katarzyna Kawa	159	8

• ¹ Rankings are as of 18 October 2021.

The following players received wildcards into the singles main draw:

• Reese Brantmeier
• Maria Kononova
• Maria Mateas
• Alana Smith

The following player received entry using a protected ranking:

• Han Na-lae

The following players received entry from the qualifying draw:

• Sophie Chang
• Ellie Douglas
• Katarina Kozarov
• Ashlyn Krueger
• Elizabeth Mandlik
• Whitney Osuigwe
• Aldila Sutjiadi
• Amy Zhu

• Misaki Doi def. Harriet Dart, 7–6^(7–5), 6–2

• Giuliana Olmos / Marcela Zacarías def. Misaki Doi / Katarzyna Kawa, 7–5, 1–6, [10–5]

• 2021 Christus Health Pro Challenge at ITFtennis.com
• Official website