Source: Soccerway Rules for classification: 1) Points; 2) Head-to-Head points; 3) Head-to-Head goal difference; 4) Head-to-Head goals scored; 5) Head-to-Head away goals scored; 6) Goal difference; 7) Goals scored. (Note: Head-to-head record is used only after all the matches between the teams in question have been played). (C) Champions Notes:
^ abcdThe 2021–22 Egyptian Premier League was not finished by the CAF deadline. As a result, the Egyptian Football Association announced that Zamalek and Al Ahly, who were at first and second place after 24 rounds respectively, represented Egypt in the 2022–23 CAF Champions League. Meanwhile, Future and Pyramids FC, who were at third and fourth place after 24 rounds respectively, represented Egypt in the 2022–23 CAF Confederation Cup.
^ abHead-to-Head points: Tala'ea El Gaish 6, Future 0.