The Knights entered the season as defending champions, and continuing their winning traditions by going undefeated in their first ten games. Eventually, they would clinch the top seed in the North Division with a record of 26–4. The twenty-six regular season wins is a record for most regular season wins in a single season, a record San Juan shares with the Davao Occidental Tigers this season and the Pampanga Giant Lanterns in 2023 and 2024.
The Knights began their playoff campaign with back-to-back sweeps against the Pasay Voyagers and Pampanga Giant Lanterns before meeting in the division finals against the Makati Super Crunch. The series was tied at 1–1 before the COVID-19 pandemic suspended the season for one year. Once play resumed in 2021, San Juan would beat Makati by a 77-point lead to advance to the national finals against the rival Davao Occidental Tigers in a rematch of last season's series. Unfortunately for the Knights, they would lose the series this time around in four games, ending their title defense.[1]
Source: Standings Rules for classification: 1) Wins; 2a) If two teams are tied, head-to-head match-up; 2b) If three or more teams are tied, head-to-head point quotient; 3) overall point quotient; 4) coin toss.