Singles
2018 Morelos Open
Final
Champion	Dennis Novikov
Runner-up	Cristian Garín
Score	6–4, 6–3
Events
Singles Doubles
← 2017 · Morelos Open · 2019 →

Alexander Bublik was the defending champion but chose not to defend his title.

Dennis Novikov won the title after defeating Cristian Garín 6–4, 6–3 in the final.

	Semifinals							Final
	6/WC	Thanasi Kokkinakis
		Cristian Garín	w/o
									Cristian Garín	4	3
								3	Dennis Novikov	6	6
	3	Dennis Novikov	6	6
	7	Peđa Krstin	1	4

	First round							Second round							Quarterfinals							Semifinals
	1	A Martin	6	5	7
		R Quiroz	2	7	5			1	A Martin	6	6
		C Eubanks	6	6					C Eubanks	4	2
		N Scholtz	3	4											1	A Martin	6	67	2
		DE Galán	6	0											6/WC	T Kokkinakis	3	79	6
		J Hernández-Fernández	1	0r					DE Galán	64	5
		Carlos Boluda-Purkiss	2	64				6/WC	T Kokkinakis	77	7
	6/WC	T Kokkinakis	6	77																		6/WC	T Kokkinakis
	4	E King	61	6	6																		C Garín	w/o
		R Statham	77	3	3			4	E King	3	64
		M Matosevic	2	4					C Garín	6	77
		C Garín	6	6												C Garín	6	3	6
	WC	L Patiño	0	2											8	D Popko	1	6	1
		A González	6	6					A González	1	3
		S Diez	6	2	2			8	D Popko	6	6
	8	D Popko	4	6	6

	First round							Second round							Quarterfinals							Semifinals
	5	M Arévalo	4	7	66
	Q	S Fanselow	6	5	78			Q	S Fanselow	4	4
		A Sarkissian	6	6					A Sarkissian	6	6
	WC	M Sánchez	4	4												A Sarkissian	1	64
		J Choinski	4	3											3	D Novikov	6	77
		A Pavić	6	6					A Pavić	4	67
		R Ortega Olmedo	62	7	4			3	D Novikov	6	79
	3	D Novikov	77	5	6																	3	D Novikov	6	6
	7	P Krstin	6	6																		7	P Krstin	1	4
	WC	T Hank	3	0				7	P Krstin	65	6	6
		A Krajicek	5	0r				Q	R Cid Subervi	77	3	0
	Q	R Cid Subervi	7	1											7	P Krstin	6	6
		M Vilella Martínez	4	6	4										2	K King	4	4
	Q	G López Villaseñor	6	4	6			Q	G López Villaseñor	1	1
	Q	E Gómez	4	3				2	K King	6	6
	2	K King	6	6

• Main draw
• Qualifying draw