The 2018–19 season was Frosinone Calcio's second-ever season in Serie A. The club were promoted as champions of Serie B at the end of the 2017–18 season, after spending two seasons in the second division following their maiden Serie A campaign in 2015–16. Frosinone competed in Serie A and the Coppa Italia.
Source: Serie A, Soccerway Rules for classification: 1) Points; 2) Head-to-head points; 3) Head-to-head goal difference; 4) Goal difference; 5) Goals scored; 6) Draw. (Note: Head-to-head record is used only after all the matches between the teams in question have been played).[25] (R) Relegated Notes:
^Positions determined by head-to-head points: Parma: 9 pts; Cagliari: 7 pts; Fiorentina: 1 pt.
^ abGenoa finished ahead of Empoli on head-to-head points: Genoa 2–1 Empoli, Empoli 1–3 Genoa.
^Chievo were deducted 3 points after being found guilty of false accounting.[24]