The 2012 Three Days of De Panne (Dutch: KBC Driedaagse van De Panne-Koksijde 2012) is the 36th edition of the Three Days of De Panne, an annual bicycle race. Taking part in and around the De Panne region of West Flanders, it began in Middelkerke on 27 March and will finish in De Panne two days later. The 544.5 km long stage race contains four stages, with two held on the final day. It is part of the 2012 UCI Europe Tour and is rated as a 2.HC event.