Qualifying round two games were played on 28 August 2010. The round included the thirty winners from qualifying round one, plus sixty-six new teams that entered at this level.
The draw for the first round was held on 31 August 2010.[2] Games were held on 11 September 2010. Thirty-two new entrants joined the forty-eight winners from qualifying round two.
The draw for the third round was held on 4 October 2010.[4] The twelve teams competing in the 2010–11 Welsh Premier League entered the competition at this stage. Starting with this round, teams are no longer divided into north and south divisions. Games will be played on 6 November 2010, with the exception of the Airbus UK Broughton/The New Saints match, which took place on 5 November 2010, and the postponed Llanelli/Aberystwyth Town match, which took place on 13 November 2010.
The draw for the fourth round was held on 13 November 2010.[5] Entering this round were the 16 winners from the previous round. The matches are scheduled to take place on 29 January 2011.