Women's singles
2008 ECM Prague Open
Final
Champion	Vera Zvonareva
Runner-up	Victoria Azarenka
Score	7–6(2), 6–2
Events
Singles men women Doubles men women
← 2007 · ECM Prague Open · 2009 →

The women's singles of the 2008 ECM Prague Open tournament was played on clay in Prague, Czech Republic.

Akiko Morigami was the defending champion, but chose not to participate that year.

Vera Zvonareva won in the final 7–6(2), 6–2, against Victoria Azarenka.

	Semifinals							Final
	1	Vera Zvonareva	6	6
	4	Katarina Srebotnik	2	4
								1	Vera Zvonareva	7	6
								3	Victoria Azarenka	62	2
	3	Victoria Azarenka	6	6
	7	Klára Zakopalová	3	2

	First round							Second round							Quarterfinals							Semifinals
	1	V Zvonareva	6	6
	LL	L Hradecká	2	3				1	V Zvonareva	w/o
		M Shaughnessy	1	3				WC	M Rybáriková
	WC	M Rybáriková	6	6											1	V Zvonareva	6	6
		R Vinci	6	6												R Vinci	1	2
	WC	Kr Plíšková	2	0					R Vinci	6	6
		J Craybas	6	6					J Craybas	4	4
	5	K Knapp	4	2																		1	V Zvonareva	6	6
	4	K Srebotnik	6	6																		4	K Srebotnik	2	4
		Y Meusburger	0	0				4	K Srebotnik	6	6
	Q	J Pandžić	0	2				Q	M Czink	0	2
	Q	M Czink	6	6											4	K Srebotnik	7	4	6
		S Arvidsson	3	7	2											I Benešová	5	6	2
		I Benešová	6	5	6				I Benešová	6	4	6
		A Amanmuradova	6	6					A Amanmuradova	2	6	3
	6	M Krajicek	4	3

	First round							Second round							Quarterfinals							Semifinals
	8	K Kanepi	7	6
		K Šprem	5	0				8	K Kanepi	6	3	5
	WC	Ka Plíšková	6	6				WC	Ka Plíšková	1	6	7
	Q	A Molik	4	4											WC	Ka Plíšková	2	1
		E Dzehalevich	1	6	5										3	V Azarenka	6	6
		T Poutchek	6	4	7				T Poutchek	2	2
		P Kvitová	3	4				3	V Azarenka	6	6
	3	V Azarenka	6	6																		3	V Azarenka	6	6
	7	K Zakopalová	6	6																		7	K Zakopalová	3	2
		S Errani	1	3				7	K Zakopalová	6	1	6
		V Dushevina	6	6					V Dushevina	4	6	3
		M Müller	0	2											7	K Zakopalová	7	6
	Q	E Ivanova	1	65											2	S Pe'er	65	2
		T Pironkova	6	7					T Pironkova	5	2
		A Lapushchenkova	5	5				2	S Pe'er	7	6
	2	S Pe'er	7	7

• Draw and Qualifying Draw