The 2005 Western Carolina Catamounts team represented Western Carolina University as a member of the Southern Conference (SoCon) in the 2005 NCAA Division I-AA football season. The Catamounts were led by fourth-year head coach Kent Briggs and played their home games at Bob Waters Field at E. J. Whitmire Stadium. They finished the season 5–4 and 4–3 in SoCon play to place fourth.

Date	Opponent	Site	Result	Attendance
September 1	Mars Hill*	Bob Waters Field at E. J. Whitmire Stadium Cullowhee, NC	W 21–7	7,425
September 10	No. 2 Furman	Bob Waters Field at E. J. Whitmire Stadium Cullowhee, NC	W 41–21	9,847
September 17	at Cincinnati*	Nippert Stadium Cincinnati, OH	L 3–7	22,637
September 24	at Nicholls State*	John L. Guidry Stadium Thibodaux, LA	Cancelled
October 1	The Citadel	Bob Waters Field at E. J. Whitmire Stadium Cullowhee, NC	L 7–17	10,067
October 8	Georgia Southern	Allen E. Paulson Stadium Statesboro, GA	L 7–45	14,156
October 22	at Chattanooga	Finley Stadium Chattanooga, TN	W 38–20	6,012
October 29	Elon	Bob Waters Field at E. J. Whitmire Stadium Cullowhee, NC	W 31–26	10,137
November 5	Wofford	Bob Waters Field at E. J. Whitmire Stadium Cullowhee, NC	W 24-0	8,021
November 12	at No. 8 Appalachian State	Kidd Brewer Stadium Boone, NC (Battle for the Old Mountain Jug)	L 7–35	25,584
*Non-conference game Homecoming Rankings from The Sports Network Poll released prior to the game

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