During the 2005–06 Dutch football season, PSV competed in the Eredivisie.
Season summary
Despite the loss of several key players following their unexpected run to the UEFA Champions Leaguesemi-final, PSV secured a second successive Eredivise title. However, they were unable to defend the KNVB Cup, losing to Ajax in the final, and were knocked out in the Champions Leaguefirst knockout round by Lyon.