The 2000 Thai Premier League consisted of 12 teams. The bottom club would be relegated to the Thailand Division 1 League. The club that came 11th would play in a relegation / promotion match against the club that came second in the Thailand Division 1 League.
Thai Farmers Bank would withdraw from the league at the end of the season due to the Asian financial crisis that initial struck in 1998. The effects would spread across Asia and many clubs now came under a huge financial burden.