The 1959 San Francisco State Gators football team represented San Francisco State College—now known as San Francisco State University—as a member of the Far Western Conference (FWC) during the 1959 college football season. Led by tenth-year head coach Joe Verducci, San Francisco State compiled an overall record of 10–0 with a mark of 5–0 in conference play, winning the FWC title for the fourth consecutive season. For the season the team outscored its opponents 302 to 85. The Gators played home games at Cox Stadium in San Francisco.
^This was the fifth annual game against San Quentin Prison. All of the games were held within the walls of the prison itself.
^A game against Occidental had been scheduled for this date. However, several members of the Occidental team came down with food poisoning, so a second game against San Quentin Prison was scheduled.
^This stadium is the predecessor to the current Mackay Stadium, which was opened for the 1966 season.[1]