The 1949 Mexican League season was the 25th season in the history of the Mexican League. It was contested by eight teams. Sultanes de Monterrey won their third championship in a row and fourth in their history after defeating Unión Laguna de Torreón in the Final Series, led by manager Lázaro Salazar.[1]
The season was contested in a split-season format, where the winner of each one of the two halves of the tournament faced each other in the Final Series to determine the champion. Monterrey won the first half with a 25–18 record, while Torreón won the second half with a 29–13 record. The Sultanes sweeped Unión Laguna in four games to claim the championship.[2]