Second-seeded Pauline Betz defeated first-seeded Louise Brough 4–6, 6–1, 6–4 in the final to win the women's singles tennis title at the 1942 U.S. National Championships.[1][2]
The eight seeded U.S. players are listed below. Sarah Palfrey Cooke is the champion; others show in brackets the round in which they were eliminated.[3]