The following lists events that happened during the 1660s in South Africa.

• The Dutch East India Company imports the first horses into the Cape from Batavia
• Jan Danaert leads a horseback expedition from the Cape settlement to the east and reaches what he names the Olifants River
• Pieter Everaert leads an unsuccessful horseback expedition from the Cape settlement to the north in an attempt to locate the land of the Namaqua

• Pieter Cruythoff is sent out from the Cape settlement to investigate the suitability of the interior for agriculture

• 7 May - Jan van Riebeeck leaves the Cape on promotion to a position on the Council of Justice in Batavia
• 9 May - Zacharias Wagenaer succeeds Van Riebeeck as Commander of the Cape

• 4 March - the Prince Edward Islands were discovered by Barent Barentszoon Lam of the Dutch East India Company ship Maerseveen, and named them Maerseveen (Marion) and Dina (Prince Edward).^[1]
• Settler outposts are established in the Hottentots Holland and Saldanha Bay areas

• 26 August - Isbrand Goske arrives at the Cape as Commissioner, and was instructed to select a site for the Castle of Good Hope

• 18 August - The first Dutch Reformed Church congregation is founded at the Cape and J. van Arkel is appointed the first minister

• Settlements in Saldanha Bay and Vishoek are established
• The first Calvinist church built in the Cape
• 2 January - Work commenced on a fortress, known as the Castle of Good Hope, which replaced the previous wooden fort built by Jan van Riebeeck and his men
• 24 October - Cornelis van Quaelberg is appointed Commander of the Cape

• The first Malays arrive as slaves

• Hieronimus Cruse explores the southeast coast as far as Mossel Bay
• 16 June - Jacob Borghorst is appointed Commander of the Cape

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• 1662 - Doman and Autsumao, leaders of the Khoikhoi and interpreters dies
• 1668 - Zacharias Wagenaer, Commander of the Cape, dies

See Years in South Africa for list of References