15,16-Dihydroxy-α-eleostearic acid

15,16-Dihydroxy-α-eleostearic acid
Names

Preferred IUPAC name (9Z,11E,13E)-15,16-Dihydroxyoctadeca-9,11,13-trienoic acid
Identifiers
CAS Number	1083078-83-4^Y
3D model (JSmol)	Interactive image
ChemSpider	57558074
PubChem CID	25156647
CompTox Dashboard (EPA)	DTXSID10648912
InChI InChI=1S/C18H30O4/c1-2-16(19)17(20)14-12-10-8-6-4-3-5-7-9-11-13-15-18(21)22/h4,6,8,10,12,14,16-17,19-20H,2-3,5,7,9,11,13,15H2,1H3,(H,21,22)/b6-4-,10-8+,14-12+ Key: OBMDTPZEEDLBKM-ZMLXCLEUSA-N
SMILES OC(CCCCCCC/C=C\C=C\C=C\C(O)C(O)CC)=O
Properties
Chemical formula	C₁₈H₃₀O₄
Molar mass	310.434 g·mol⁻¹
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Y verify (what is ^YN ?) Infobox references

15,16-Dihydroxy-α-eleostearic acid, or 15,16-Dihydroxy-(9Z,11E,13E)-9,11,13-octadecatrienoic acid, is an organic compound with formula C
₁₈H
₃₀O
₄, or H₃C-CH₂-(-CH(OH)-)₂(-CH=CH-)₃-(-CH₂-)₇-(C=O)OH. It can be seen as derived from α-eleostearic acid by the replacement of two hydrogen atoms by two hydroxyl (OH) groups.

The compound is found in the pulp and seeds of bitter melons (the fruits of Momordica charantia). It has been found to induce apoptosis in HL60 leukemia cells in vitro at a concentration of 160 μM, although it is less potent in this regard than the unsubstituted α-eleostearic acid (also found in the seed oil). While α-eleostearic acid has been found to prevent carcinogenesis in rats, this derivative does not seem to have that effect.^[1]

The compound can be extracted from the fruit with ethanol, and is soluble in ethyl acetate but not in water or acetone.

References

^ Masuko Kobori, Mayumi Ohnishi-Kameyama, Yukari Akimoto, Chizuko Yukizaki and Mitsuru Yoshida (2008) α-Eleostearic Acid and Its Dihydroxy Derivative Are MajorApoptosis-Inducing Components of Bitter Gourd. Journal of Agricultural and Food Chemistry, volume 56, issue 22, pages 10515–10520. doi:10.1021/jf8020877

Read other articles:

Deputi Bidang Koordinasi Pengelolaan Energi, Sumber Daya Alam, dan Lingkungan Hidup

Deputi Bidang Koordinasi Pengelolaan Energi, Sumber Daya Alam, dan Lingkungan Hidup Kementerian Koordinator Bidang Perekonomian Republik IndonesiaGambaran umumDasar hukumPeraturan Presiden Nomor 8 Tahun 2015Susunan organisasiDeputiMontty Girianna[1]Kantor pusatGedung Ali Wardhana Jl. Lapangan Banteng Timur No.2-4, Jakarta Pusat 10710[2]Situs webwww.ekon.go.id Deputi Bidang Koordinasi Pengelolaan Energi, Sumber Daya Alam, dan Lingkungan Hidup merupakan unsur pelaksana pada...

Printemps Strasbourg

Si ce bandeau n'est plus pertinent, retirez-le. Cliquez ici pour en savoir plus. Certaines informations figurant dans cet article ou cette section devraient être mieux reliées aux sources mentionnées dans les sections « Bibliographie », « Sources » ou « Liens externes » (mai 2021). Vous pouvez améliorer la vérifiabilité en associant ces informations à des références à l'aide d'appels de notes. Printemps StrasbourgFaçade extérieure de Printemps S...

イスラームにおける結婚

イスラームにおける結婚（イスラームにおけるけっこん）とは、二者の間で行われる法的な契約である。新郎新婦は自身の自由な意思で結婚に同意する。口頭または紙面での規則に従った拘束的な契約は、イスラームの結婚で不可欠だと考えられており、新郎と新婦の権利と責任の概要を示している[1]。イスラームにおける離婚は様々な形をとることができ、個�...

ロバート・デ・ニーロ

ロバート・デ・ニーロRobert De Niro 2011年のデ・ニーロ生年月日 (1943-08-17) 1943年8月17日（80歳）出生地アメリカ合衆国・ニューヨーク州ニューヨーク市身長 177 cm職業俳優、映画監督、映画プロデューサージャンル映画、テレビドラマ活動期間 1963年 -配偶者ダイアン・アボット（1976年 - 1988年）グレイス・ハイタワー（1997年 - ）主な作品『ミーン・ストリート』（1973年）...

Speaker of the Dewan Rakyat

Presiding officer of the Malaysian lower house of Parliament Speaker of the Dewan RakyatYang di-Pertua Dewan RakyatIncumbentJohari Abdulsince 19 December 2022Dewan RakyatStyleYang Berhormat Tuan Yang di-Pertua (formal) Tuan Speaker/Tuan Pengurusi (informal and within the House)Member ofCommittee of Selection, Standing Orders Committee, House Committee, Committee of PrivilegesReports toDewan RakyatAppointerElected by members of the Dewan RakyatTerm lengthElected at the start of each Parli...

Țara Hațegului

Area of Romania Țara Hațegului (Hațeg Land; German: Wallenthal, Hungarian: Hátszegvidék, Latin: terra Harszoc) is a historical and ethnographical area in Hunedoara County, Romania, in the south-western corner of Transylvania. It is centered in the town of Hațeg. Hațeg (Hatzag) Land on a map from 1607. Țara Hațegului is located in the Depression of Hațeg. Here there are: the site of Ulpia Traiana Sarmizegetusa (the capital of the Roman Dacia, established in the 2nd century A.D.), the...

RB-64

Chemical compound RB-64Legal statusLegal status Legal/Uncontrolled Identifiers IUPAC name Methyl (2S,4aR,6aR,7R,9S,10aS,10bR)-2-(furan-3-yl)-6a,10b-dimethyl-4,10-dioxo-9-(2-thiocyanatoacetyl)oxy-2,4a,5,6,7,8,9,10a-octahydro-1H-benzo[f]isochromene-7-carboxylate PubChem CID73347341ChemSpider30812525 YChEMBLChEMBL2381583 YChemical and physical dataFormulaC24H27NO8SMolar mass489.54 g·mol−13D model (JSmol)Interactive image SMILES C[C@@]12CC[C@H]3C(=O)O[C@@H](C[C@@]3([C@H]1C(=O)[C...

Admiral Sportswear

English sportswear company AdmiralProduct typeSportswear Apparel Sports EquipmentOwnerAdmiral Sportswear Ltd.[1]CountryEnglandMarketsWorldwidePrevious ownersCook and Hurst (1914)TaglineWorn by ChampionsWebsiteadmiralsports.comCompanyFounded1914; 110 years ago (1914) by Cook & Hurst Ltd.[2]HeadquartersAltrincham, Manchester Admiral is an English sportswear brand, with a manufacturing emphasis on clothing for association football. Founded in 1914 in Leicest...

世界政區索引

此條目可能包含不适用或被曲解的引用资料，部分内容的准确性无法被证實。 (2023年1月5日)请协助校核其中的错误以改善这篇条目。详情请参见条目的讨论页。各国相关主題列表索引国内生产总值石油储量国防预算武装部队（军事）官方语言人口統計人口密度生育率出生率死亡率自杀率谋杀率失业率储蓄率识字率出口额进口额煤产量发电量监禁率死刑国债 ...

Communes du canton de Neuchâtel

Carte du canton de Neuchâtel présentant sa division en communes en 2021. Cet article présente l'évolution des communes du canton de Neuchâtel. Les communes politiques neuchâteloises modernes datent de la deuxième moitié du 19e siècle et reprennent des structures urbaines ou villageoises précédentes. Histoire Communautés, corporations et bourgeoisies d'Ancien Régime Carte des subdivisions de la Principauté de Neuchâtel et Valangin en 1747 par Daniel de Lafeuille. Représentation...

نوكيا لوميا 820

نوكيا لوميا 820الشعارمعلومات عامةالماركة نوكيا النوع هاتف ذكي الصانع نوكياعائلة المنتج لومياالسعر المبدئي 900٬000 روبية إندونيسية[1] موقع الويب http://www.nokia.com/global/products/phone/lumia820/أهم التواريختاريخ الإصدار 7 نوفمبر 2012توقف الإصدار 2014 الوظائفالشاشة شاشة لمسالكاميرا - الخلفية:8 مي...

List of judgments of the Constitutional Court of South Africa delivered in 2017

Judgments of the Constitutional Courtof South Africa 1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 2023 2024 vte The table below lists the judgments of the Constitutional Court of South Africa delivered in 2017. The members of the court at the start of 2017 were Chief Justice Mogoeng Mogoeng and judges Edwin Cameron, Johan Froneman, Chris Jafta, Sisi Khampepe, Mbuyiseli Madlanga, Nonkosi Mhlantla, B...

Religion in Kazakhstan

Religion in Kazakhstan (2023 Census)[1] Islam (mainly Sunni) (74%) Christianity (14%) Atheism (2%) Other or undeclared (11.25%) According to various polls, the majority of Kazakhstan's citizens, primarily ethnic Kazakhs, identify as Sunni Muslims.[2][3] In 2020, Shia Muslims made up 0.55% of the population.[4] According to the estimate by the Pew Research Center, 75% of the population practices the religion of Islam...

Ian Charleson

Scottish actor Ian CharlesonCharleson as Eric Liddell in Chariots of FireBorn(1949-08-11)11 August 1949Edinburgh, ScotlandDied6 January 1990(1990-01-06) (aged 40)London, EnglandResting placePortobello Cemetery, Edinburgh, ScotlandEducationUniversity of Edinburgh (MA)London Academy of Music and Dramatic ArtOccupation(s)Actor, singerYears active1972–1989 Ian Charleson (11 August 1949 – 6 January 1990) was a Scottish stage and film actor. He is best known internationally for his st...

Airco DH.3

Airco DH.3Il prototipo Airco DH.3 con le ali ripiegateDescrizioneTipobombardiere Equipaggio3 ProgettistaGeoffrey de Havilland Costruttore Airco Data ordine1916 Data primo volo1º gennaio 1917[1] Data entrata in servizio1917 Data ritiro dal servizio1917 Esemplari2[2] Altre variantiAirco DH.10 Dimensioni e pesiTavole prospettiche Lunghezza11,23 m (36 ft 10 in) Apertura alare18,54 m (60 ft 10 in) Altezza4,42 m (14 ft 6 in) Superficie alare73,67 m² (793 ft²) Peso a vuoto1 8...

Sex hormone-binding globulin

Human glycoprotein that binds to androgens and estrogens SHBGAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1LHW, 1D2S, 1F5F, 1KDK, 1KDM, 1LHN, 1LHO, 1LHU, 1LHVIdentifiersAliasesSHBG, ABP, SBP, TEBG, sex hormone binding globulin, Sex hormone-binding globulinExternal IDsOMIM: 182205; MGI: 98295; HomoloGene: 813; GeneCards: SHBG; OMA:SHBG - orthologsGene location (Human)Chr.Chromosome 17 (human)[1]Band17p13.1Start7,613,946 bp[1]End7,633,382 bp[1]Ge...

Incense trade route

Trade road that connects Mediterranean ports to India via Africa and Arabia Satellite view of the red sea and adjacent lands, the incense trade, connecting Egypt to the incense-producing lands, depended heavily on navigation along the Red Sea. The incense trade route was an ancient network of major land and sea trading routes linking the Mediterranean world with eastern and southern sources of incense, spices and other luxury goods, stretching from Mediterranean ports across the Levant and Eg...

Ciecholub railway station

Railway station in Pomeranian Voivodeship, Poland CiecholubGeneral informationLocationCiecholubPolandOwned byPolskie Koleje Państwowe S.A.Line(s)405: Piła Główna - Ustka UroczyskoHistoryPrevious namesTechlippServices Preceding station Polregio Following station Przytockotowards Miastko, Szczecinek or Chojnice PR Biesowicetowards Słupsk Ciecholub is a PKP railway station in Ciecholub (Pomeranian Voivodeship), Poland. Lines crossing the station Start station End station Line type Piła Ust...

地蔵盆

村の辻の地蔵堂（地蔵盆の宵）前に積まれている供え物は、やってきた子供達に配られる。電球ではなく、蝋燭の入った提灯はほの暗い地蔵盆の提灯宿場一夜夢街道（兵庫県篠山市）地蔵盆（じぞうぼん）は、地蔵菩薩の縁日で、厳密には毎月24日であるが、一般的には、その中で特にお盆にも近い旧暦7月24日のものをいう。ただし、寺院に祀られている地蔵ではなく...

بروك هايلاند

بروك هايلاند الإحداثيات 33°25′43″N 86°41′35″W / 33.428571°N 86.693028°W / 33.428571; -86.693028 [1] تقسيم إداري البلد الولايات المتحدة[2] التقسيم الأعلى مقاطعة شيلبي خصائص جغرافية المساحة 7.392834 كيلومتر مربع7.467362 كيلومتر مربع (1 أبريل 2010)[3] ارتفاع 202 مت�...

PROFILPELAJAR.COM