Die nachfolgenden Routes in Prince Edward Island stehen unter Verwaltung des Prince Edward Island Department of Transportation and Infrastructure Renewal. In Prince Edward Island werden die Highways zum einen in Primary Highways, die das Rückgrat des Straßennetzes bilden, und in Secondary Highways, die das Umland erschließen, unterteilt.

Zeichen	Nummer	Name	Beginn	Ende	Länge in Kilometern
	1	Trans-Canada Highway	Confederation Bridge	Wood Islands	120
	1A		Albany Corner	Travelers Rest	20
	2	The All Weather Highway Veteran’s Memorial Highway	Tignish	Souris	216
	3		Cherry Valley	Georgetown	33
	4	The Seven Mile Rd	Wood Islands	Dingwells Mills	63

Zeichen	Nummer	Name	Beginn	Ende	Länge in Kilometern
	5		Mt Albion	Cardigan	28
	6		Bedford	Kensington	68
	7		Milton	Oyster Bed Bridge	10
	8		Ross Corner	New London	22
	9		Long Creek	Brookfield	18
	10		Bedeque	Tryon	23
	11		Summerside	Mt Pleasant	66
	12		Miscouche	North Cape	53
	13		Crapaud	Cavendish	38
	14		Coleman	Tignish	82
	15		Sherwood	Brackley Beach	20
	16		Souris	St. Peters	75
	16A		South Lake	North Lake	4
	17		Murray River	Montague	37
	17A		Cambridge	Sturgeon	7
	18		High Bank	Murray River	24
	18A		White Sands	Murray Harbour	3
	19		Desable	Cornwall	45
	19A		Canoe Cove	New Dominion	5
	20		Kensington	New London	32
	21		Fanning Brook	Bunbury	31
	22		Victoria Cross	Mount Stewart	29
	23		Wood Islands	Orwell	22
	24		Murray River	Vernon River	29
	25		Marshfield	Stanhope	18
	25A		Covehead	West Covehead	2
	26		Cross Roads	Mount Albion	11