Histiocitosi de cèl·lules de Langerhans

Plantilla:Infotaula malaltiaHistiocitosi de cèl·lules de Langerhans
Un pacient amb la malaltia de Hand-Schüller-Christian que és un subtipus d’histiocitosi de cèl·lules de Langerhans.
Lesions estelades de la histiocitosi de cèl·lules de Langerhans modifica
Tipushistiocitosi i malaltia Modifica el valor a Wikidata
EpònimCèl·lula de Langerhans Modifica el valor a Wikidata
Especialitatoncologia Modifica el valor a Wikidata
Classificació
CIM-112B31.2 Modifica el valor a Wikidata
CIM-10C96.6 Modifica el valor a Wikidata
CIM-9202.5 Modifica el valor a Wikidata
CIM-O9752/3, 9751/1 i 9751/3 Modifica el valor a Wikidata
Recursos externs
OMIM604856 i 246400 Modifica el valor a Wikidata
DiseasesDB5906 Modifica el valor a Wikidata
eMedicine1100579 Modifica el valor a Wikidata
MeSHD006646 Modifica el valor a Wikidata
Orphanet389 Modifica el valor a Wikidata
UMLS CUIC0019621 i C0023381 Modifica el valor a Wikidata
DOIDDOID:2571 Modifica el valor a Wikidata

La histiocitosi de cèl·lules de Langerhans (HCL) és un càncer rar que implica la proliferació clonal de cèl·lules de Langerhans, cèl·lules anormals derivades de medul·la òssia i capacitats de migració de la pell als ganglis. Els símptomes van des de les aïllades dels ossos fins a malalties multisistèmiques. La HCL forma part de grup de síndromes anomenades histiocitosis, que es caracteritzen per una proliferació histiocítica anormal (terme arcaic per cèl·lules dendrítiques i macròfags activats). Aquests malalties estan relacionades amb altres formes de proliferació anormals dels leucòcits, com ara leucèmies i limfomes.

També rep el nom, d'histiocitosi X.

Tipus

La HCL es divideix clínicament en tres grups:[1]

Grups Formes
Granuloma eosinofílic Crònica focal
Malaltia de Hand-Schüller-Christian Crònica disseminada
Malaltia de Letterrer-Siwe Aguda disseminada

Referències

  1. ↑ Cotran, Ramzi S.. Robbins and Cotran pathologic basis of disease. St. Louis, Mo: Elsevier Saunders, 2005, p. 701–. ISBN 978-0-8089-2302-2. 

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