PROFILPELAJAR.COM

PLP2
Identifikatori
Aliasi	PLP2
Vanjski ID-jevi	OMIM: 300112 MGI: 1298382 HomoloGene: 2003 GeneCards: PLP2
Lokacija gena (čovjek)
Hrom.	Hromosom X
Kraj	49,175,235 bp
Lokacija gena (miš)
Hrom.	Hromosom X (miš)
Kraj	7,537,629 bp
Obrazac RNK ekspresije
	Više referentnih podataka o ekspresiji
Ontologija gena
Molekularna funkcija	• ion transmembrane transporter activity; • GO:0001948, GO:0016582 vezivanje za proteine; • chemokine binding;
Ćelijska komponenta	• membrana; • endoplasmic reticulum membrane; • ćelijska membrana; • Endoplazmatski retikulum; • integral component of membrane;
Biološki proces	• cytokine-mediated signaling pathway; • Hemotaksija; • ion transport; • ion transmembrane transport;
	Izvori:Amigo / QuickGO
Ortolozi
	5355
	18824
	ENSG00000102007
	ENSMUSG00000031146
	Q04941
	Q9R1Q7
	NM_002668
	NM_019755
	NP_002659; NP_002659.1
	NP_062729
	Wikipodaci
Pogledaj/uredi – čovjek	Pogledaj/uredi – miš

Proteolipidni protein 2 je protein koji je kod ljudi kodiran genom PLP2.^[5]^[6]^[7]

Reference

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000102007 - Ensembl, maj 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000031146 - Ensembl, maj 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Oliva MM, Wu TC, Yang VW (maj 1993). "Isolation and characterization of a differentiation-dependent gene in the human colonic cell line HT29-18". Arch Biochem Biophys. 302 (1): 183–192. doi:10.1006/abbi.1993.1197. PMID 8470895.
^ Oliva MM, Cortese JF, Yang VW (Aug 1995). "Promoter regulation of a differentially expressed gene in the human colonic epithelial cell lines HT29-18 and HT29-18-C1". Gene. 159 (2): 151–157. doi:10.1016/0378-1119(95)00130-X. PMID 7622043.
^ "Entrez Gene: PLP2 proteolipid protein 2 (colonic epithelium-enriched)".

Dopunska literatura

Breitwieser GE; McLenithan JC; Cortese JF; et al. (1997). "Colonic epithelium-enriched protein A4 is a proteolipid that exhibits ion channel characteristics". Am. J. Physiol. 272 (3 Pt 1): C957–65. doi:10.1152/ajpcell.1997.272.3.C957. PMID 9124532.
Fisher SE; Ciccodicola A; Tanaka K; et al. (1998). "Sequence-based exon prediction around the synaptophysin locus reveals a gene-rich area containing novel genes in human proximal Xp" (PDF). Genomics. 45 (2): 340–347. doi:10.1006/geno.1997.4941. PMID 9344658.
Strausberg RL; Feingold EA; Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–16903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Wang B; Nguyen M; Breckenridge DG; et al. (2003). "Uncleaved BAP31 in association with A4 protein at the endoplasmic reticulum is an inhibitor of Fas-initiated release of cytochrome c from mitochondria". J. Biol. Chem. 278 (16): 14461–14468. doi:10.1074/jbc.M209684200. PMID 12529377.
Lee SM; Shin H; Jang SW; et al. (2004). "PLP2/A4 interacts with CCR1 and stimulates migration of CCR1-expressing HOS cells". Biochem. Biophys. Res. Commun. 324 (2): 768–772. doi:10.1016/j.bbrc.2004.09.118. PMID 15474493.
Gerhard DS; Wagner L; Feingold EA; et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–2127. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Pope SN, Lee IR (2005). "Yeast two-hybrid identification of prostatic proteins interacting with human sex hormone-binding globulin". J. Steroid Biochem. Mol. Biol. 94 (1–3): 203–208. doi:10.1016/j.jsbmb.2005.01.007. PMID 15862967.
Zhang L; Jie C; Obie C; et al. (2007). "X chromosome cDNA microarray screening identifies a functional PLP2 promoter polymorphism enriched in patients with X-linked mental retardation". Genome Res. 17 (5): 641–648. doi:10.1101/gr.5336307. PMC 1855181. PMID 17416750.
Stirling PC; Srayko M; Takhar KS; et al. (2007). "Functional interaction between phosducin-like protein 2 and cytosolic chaperonin is essential for cytoskeletal protein function and cell cycle progression". Mol. Biol. Cell. 18 (6): 2336–2345. doi:10.1091/mbc.E07-01-0069. PMC 1877119. PMID 17429077.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000102007 - Ensembl, maj 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000031146 - Ensembl, maj 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid8470895-5] Oliva MM, Wu TC, Yang VW (maj 1993). "Isolation and characterization of a differentiation-dependent gene in the human colonic cell line HT29-18". Arch Biochem Biophys. 302 (1): 183–192. doi:10.1006/abbi.1993.1197. PMID 8470895.

[pmid7622043-6] Oliva MM, Cortese JF, Yang VW (Aug 1995). "Promoter regulation of a differentially expressed gene in the human colonic epithelial cell lines HT29-18 and HT29-18-C1". Gene. 159 (2): 151–157. doi:10.1016/0378-1119(95)00130-X. PMID 7622043.

[entrez-7] "Entrez Gene: PLP2 proteolipid protein 2 (colonic epithelium-enriched)".

[1]

[2]

[3]

[4]

[5]

[6]

[7]