Michael Houghton (virolog)

Michael Houghton (virolog)
Alma materUniversity of East Anglia (BSc)
King's College London (PhD)

Michael Houghton (rođen 1949.) jeste britanski naučnik i dobitnik Nobelove nagrade. Zajedno s Qui-Lim Choo, Georgeom Kuom i Danielom W. Bradleyem, suotkrio je Hepatitis C 1989.[1] Također je 1986. suotkrio genom hepatitisa D.[2] Otkriće virusa hepatitisa C (HCV) dovelo je do brzog razvoja dijagnostičkih reagensa za otkrivanje HCV-a u zalihama krvi, što je smanjilo rizik od stjecanja HCV-a transfuzijom krvi sa svakog trećeg na oko jedan od dva miliona.[3][4] Procjenjuje se da je testiranje antitijela spriječilo najmanje 40 000 novih infekcija godišnje samo u SAD-u i mnogim drugim zemljama širom svijeta.[5]

Houghton je trenutno kanadski predsjedavajući za istraživanje izvrsnosti u virusologiji i Li Ka Shing profesor virusologije na Univerzitetu Alberta, gdje je i direktor Instituta za primijenjenu virusologiju Li Ka Shing.[6] Doprimitelj je Nobelove nagrade za fiziologiju ili medicinu za 2020. zajedno s Harveyem J. Alterom i Charlesom M. Riceom .[7][8]

Nobelova nagrada za fiziologiju ili medicinu 2020: Seminalni eksperimenti HJ Altera, M Houghtona i CM Rice koji su doveli do otkrića HCV-a kao uzročnika ne-A, ne-B hepatitisa.

Reference

  1. ^ "Isolation of a cDNA clone derived from a blood-borne non-A, non-B viral hepatitis genome". Science. 244 (4902): 359–62. april 1989. Bibcode:1989Sci...244..359C. doi:10.1126/science.2523562. PMID 2523562.
  2. ^ Wang, KS; Choo, QL; Weiner, AJ; Ou, JH; Najarian, RC; Thayer, RM; Mullenbach, GT; Denniston, KJ; Gerin, JL (9. 10. 1986). "Structure, sequence and expression of the hepatitis delta (delta) viral genome". Nature. 323 (6088): 508–14. Bibcode:1986Natur.323..508W. doi:10.1038/323508a0. PMID 3762705.
  3. ^ "Opinion: Nobel-worthy discovery right in our backyard". Canadian for Health Research. Arhivirano s originala, 14. 9. 2016. Pristupljeno 4. 9. 2016.
  4. ^ "Science world abuzz as virologist turns down Gairdner award". The Globe and Mail. Pristupljeno 10. 9. 2016.
  5. ^ Thompson, Gilbert (2014). Pioneers of Medicine Without a Nobel Prize. str. 209. ISBN 978-1-78326-386-8.
  6. ^ "MMI Faculty – Michael Houghton, PhD". Arhivirano s originala, 6. 3. 2018. Pristupljeno 13. 1. 2014.
  7. ^ "Press release: The Nobel Prize in Physiology or Medicine 2020". Nobel Foundation. Pristupljeno 5. 10. 2020.
  8. ^ Wu, Katherine J.; Victor, Daniel (5. 10. 2020). "Nobel Prize in Medicine Awarded to Scientists Who Discovered Hepatitis C Virus – Harvey J. Alter, Michael Houghton and Charles M. Rice were jointly honored for their decisive contribution to the fight against blood-borne hepatitis, a major global health problem". The New York Times. Pristupljeno 6. 10. 2020.

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