Kevin Matthews (Todd Eric Andrews), becomes a new pupil at Ralph Waldo Emerson High School. Rejected by the trendy Key Club, he instead joins the Science Club. There he accidentally discovers a number of vials that were made by former student Barney Springboro (from the original film) behind a hidden panel in the lab.
After drinking the contents, Kevin develops psychokinetic powers. He amuses himself by lifting girls' dresses and humiliating the Key Club jocks, becoming popular in the process. However, the Key Club plots a cruel revenge.