Powell starred in The Great Ziegfeld, (1936), opposite his The Thin Man co-star, Myrna Loy, who played Ziegfeld's wife, Billie Burke. In 1937, Powell received his second Academy Award nomination for the comedy My Man Godfrey.[10]
In 1935, he starred with Jean Harlow in Reckless. In 1936, Harlow and Powell appeared in Libeled Lady, and they became romantically involved off-set. He gave her a handsome ring, but did not ask her to marry him, so she referred to it as her "unengagement ring". Powell had been unhappy with his previous marriage to popular actor Carole Lombard, and this apparently kept him from entering a similar arrangement with Harlow, who was a sex symbol to the film-going public during that time. They kept company but did not live together. Harlow fell ill from undiagnosed kidney failure while working on a film with Clark Gable, and died before the film was completed, from uremia, at age 26 in June 1937.[11]
Powell received his third Academy Award nomination in 1947 for his role as Clarence Day Sr. in Life with Father.[12] His last film was playing the character Doc in 1955's Mister Roberts.
On April 15, 1915, Powell married Eileen Wilson, who was born Julia Mary Tierney. The couple had a son, William David Powell. They divorced in 1930. Powell's son became a television writer and producer before a period of ill health and depression led to his suicide in 1968.[13]
On June 26, 1931, Powell married actress Carole Lombard. They divorced in 1933, but starred in My Man Godfrey three years later. Powell was devastated by her death in an airplane crash in 1942.[14] He was romantically involved with Jean Harlow, his co-star in Reckless (1935), until her unexpected death from illness in 1937.[15][16] On January 6, 1940, three weeks after they met, Powell married his third wife, actress Diana Lewis, who cancelled her film career to be his full-time wife. They remained married until his death in 1984.[17]
In March 1938, Powell was diagnosed with rectal cancer.[4][20] He underwent surgery and experimental radium treatment, which put the disease in full remission within two years. Given his own health and sorrow over Jean Harlow's death, Powell did not undertake any film roles for more than a year during this period.[21]
^"Pennsylvania Births and Christenings, 1709–1950", Horatio Powell, July 29, 1892, son of H. W. Powell and Nettie B. Powell; Pittsburgh, Allegheny County, Pennsylvania. Record accessed via FamilySearch archives, Salt Lake City, Utah, January 31, 2022.
^ ab"Obituaries: William Powell, star of 'Thin Man' films", Chicago Tribune, March 6, 1984, p. N6. Retrieved via ProQuest Historical Newspapers through subscription access at The University of North Carolina at Chapel Hill Library, January 31, 2022.
^Brooks, Patricia; Brooks, Jonathan (2006). "Chapter 8: East L.A. and the Desert". Laid to Rest in California: A guide to the cemeteries and grave sites of the rich and famous. Guilford, CT: Globe Pequot Press. pp. 240–42. ISBN978-0762741014. OCLC70284362.