William Leigh (1550–1639) was an English clergyman and royal tutor.

William Leigh may also refer to:

• William Leigh (MP), member of Parliament for Cumberland in 1399 and 1414
• William Leigh (Dean of Hereford) (1752–1809), Anglican priest
• William Henry Leigh (merchant) (1781–1818), merchant and former colonial official in Sierra Leone
• William Leigh (judge) (1783–1871), American jurist
• William Henry Leigh, 2nd Baron Leigh (1824–1905), British politician
• William Leigh, ship's surgeon, early settler and landowner at Clarendon, South Australia c.1846
• William Robinson Leigh (1866–1955), American artist
• William Colston Leigh Sr. (1901–1992), American businessman, created one of the world's leading speakers' agencies
• William Gerard Leigh (1915–2008), member of the British Life Guards and major figure in the polo world

• William Lee (disambiguation)
• All pages with titles containing William Leigh

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