He was the second son of William Leslie, fifth laird of Warthill, Aberdeenshire, and his wife Anne, daughter of James Elphinstone of Glack, and great-niece of William Elphinstone, bishop of Aberdeen. He went at the age of 11 with his elder brother to King's College, Aberdeen.[1]
Leslie had relatives in Austria, the Counts Leslie, and, through their influence, he became in 1716 Bishop of Waitzen in Hungary. In favour with Emperor Joseph I, and a privy councillor, he was in 1718 translated to the see of Laibach, an appointment which carried with it the dignities of metropolitan of Carniola and prince of the Holy Roman Empire.[1]
In 1725, Bishop Leslie sent his portrait and his diploma from the university of Padua, along with some correspondence, home to his brother in Scotland. He died two years later, in 1727.[1]