The show's premise was that Reeves had been put under house arrest for "a crime he didn't commit", each show beginning with him informing listeners of a different ludicrous crime. Each episode consisted of the various events that take place in and around his house on a particular day. Regular occurrences included Reeves waking up the street and inadvertently firing objects into the local vicar's vestry in the process, reading bizarre small ads in the newspaper, watching a television programme, reading his book Nothing but the Sleuth, struggling to stop his records from jumping, and visiting the animal menagerie in his shed. He was also visited by a variety of characters such as Carl - a talkative housecall-making hairdresser (Bob Mortimer), a local vagrant just out of jail and looking for odd jobs (Noel Fielding), and his parole officer (Nancy Sorrell).
In addition to these new characters, the show also featured some characters from previous Vic and Bob series' including "Kinky" John Fowler (Bang Bang, It's Reeves and Mortimer / Catterick) and Davey Stott (Vic Reeves Big Night Out / Bang Bang, It's Reeves and Mortimer). The programme also featured Reeves practising his "club singer"-style vocals (Shooting Stars) in the bath, with the intention of getting on The X Factor.