Vern L. Schramm

Vern L. Schramm
Schramm in 2004
BornNovember 9, 1941 (1941-11-09) (age 83)
Howard, South Dakota, U.S.
Alma materSouth Dakota State University
Known forEnzyme kinetics, Kinetic isotope effect
AwardsRudi Lemberg Award, Repligen Award
Scientific career
FieldsBiochemistry
InstitutionsAlbert Einstein College of Medicine
Doctoral advisorJohn F. Morrison

Vern L. Schramm (born November 9, 1941) is a professor and Ruth Merns Chair in Biochemistry at the Albert Einstein College of Medicine of Yeshiva University.[1][2] Schramm was elected to the National Academy of Sciences in 2007.[3][4] His laboratory's research focuses on the elucidation of enzymatic mechanisms and transition state structure.[4]

This information is then used for the logical design of transition-state inhibitors which have the potential to be new biologically active agents. Some of these are in development to be drugs. Schramm's work has translated basic chemical understanding at the quantum mechanical level to a new approach to drug development.[5]

Education

Schramm earned his bachelor's degree from South Dakota State College, now South Dakota State University. He earned his master's degree in nutrition from Harvard University and his Ph.D. in the mechanism of enzyme action from the Australian National University.[4]

Career

Schramm secured a postdoctoral position at the NASA Ames Research Center after graduation. Later he joined the Temple University School of Medicine as a faculty member. In 1987 he joined the faculty at Albert Einstein College of Medicine as professor and chair of the biochemistry department.[4]

Personal Life

Schramm was diagnosed with colon cancer in 2022.

Awards and distinctions

References

  1. ^ "Einstein Faculty: Vern L. Schramm, Ph.D." Retrieved 2010-01-18.
  2. ^ "Vern L Schramm - ComBio 2009, Christchurch, New Zealand". Retrieved 2010-01-18.
  3. ^ "Einstein's Dr. Vern Schramm elected to the National Academy of Sciences". Retrieved 2010-01-18.
  4. ^ a b c d "Einstein's Dr. Vern Schramm elected to the National Academy of Sciences". Bio-Medicine. May 1, 2007. Retrieved 2010-01-18.
  5. ^ Schramm VL (2011). "Enzymatic transition states, transition-state analogs, dynamics, thermodynamics, and lifetimes". Annual Review of Biochemistry. 80: 703–32. doi:10.1146/annurev-biochem-061809-100742. PMC 5502542. PMID 21675920.
  6. ^ "Rudi Lemberg Fellow". Australian Academy of Science. January–April 2000. Retrieved 28 October 2010.
  7. ^ a b c "Vern L. Schramm, PhD Biographical Sketch" (PDF). Ann Arbor, MI. 2009. p. 4. Retrieved 18 January 2010.

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