Desai was with the famous Prabhat Film Company since it started making talkies. He acted, sang, and sometimes composed songs in Prabhat's films like Dharmatma and Sant Dnyaneshwar. After learning the craft of music composition, he stuck solely to it since the 1940s.
Desai scored music for a majority of V. Shantaram's films when the latter broke away from Prabhat to form his own film studio. Their relations soured in late 1950s after which Vasant(rao) Desai never worked for his former mentor again.
Maithreem Bhajata is a benediction composed in Sanskrit by Sant Jagadguru Shri Chandrasekharendra Saraswati of the Kanchi Mutt. The song was set to a Ragamalika by composer Shri Vasant Desai. It was rendered at the United Nations on Oct. 23, 1966 on the occasion of the UN day, by Bharat Ratna Smt. M. S. Subbulakshmi.
In Marathi, some of Desai's memorable songs are Sanga mukund kuni ha pahila, Uthi uthi Gopala from Amar Bhoopali (1951), Manuskichya shatrusange yuddha amuche suru from Chota Jawan (1963), Deh devache mandir from Preeti Sangam (1972), Ramya hi swargahuni Lanka from Swayamwar Zale Siteche (1974).[4]
Last recording
Vasant Desai went back home on December 22, 1975, after a full-day recording of a special musical programme at HMV Studios attended by high-profile musicians as it was in praise of Indira Gandhi[citation needed]. He stepped into the elevator of his apartment building and due to a technical glitch, the lift began to move, crushing him to death.[4]
