Xerri debuted in North Melbourne's four point loss against Hawthorn in the fourth round of the 2020 AFL season.[7][8] He kicked one goal, had 5 disposals and 3 tackles.[9] In September 2020, Xerri signed a new two-year contract keeping him with North Melbourne until 2022.[10] On 6 October 2021, Xerri requested a trade to St Kilda.[11] The trade failed to eventuate, and Xerri remained at North Melbourne. In 2022, Xerri signed a three-year contract extension.[12] He became North’s leading Ruck in 2023, but missed much of the season due to an ankle injury in Round One.[13]
In early 2024, Xerri injured his face in a training accident and had a plate inserted.[14]
^The 2020 season was played with 17 home-and-away matches per team (down from 22) and 16-minute quarters with time on (down from 20-minute quarters with time on) due to the impact of the COVID-19 pandemic.