Doyle was promoted to the major leagues by the Rockies on September 23, 2020.[7] He made his major league debut that night against the San Francisco Giants.
On October 21, 2021, Doyle was outrighted off of the 40-man roster.[8] He missed the entirety of the 2022 season after undergoing shoulder surgery.[9]
Doyle began the 2023 season with the Triple–A Albuquerque Isotopes, making 22 appearances and logging a stellar 1.01 ERA with 29 strikeouts and 3 saves in 26+2⁄3 innings pitched. On July 14, 2023, the Rockies selected Doyle's contract, adding him to the active roster.[10] In 15 games for Colorado, he struggled to a 6.85 ERA with 18 strikeouts across 23+2⁄3 innings of work. On November 17, Doyle was designated for assignment following the acquisition of Cal Quantrill.[11] He was non-tendered and became a free agent on November 17.
Atlanta Braves
On November 25, 2023, Doyle signed a minor league contract with the Atlanta Braves.[12] He became a free agent after the season.[13]