Lezana began his career, playing with the Santiago Lawn Tennis Club from 2013 before being signed by the Jaguares in 2016, who he played for until 2020.[2] In December 2020 he was signed by the Western Force to play in the 2021 Super Rugby AU season and Super Rugby Trans-Tasman.[3]
Lezana made his senior debut for Los Pumas on 22 November 2014, coming on as an early replacement for the injured Leonardo Senatore in an 18 -13 win over France in Paris.[4]