Water from Upnuk Lake flows about 10 miles (16 km) to join the river downstream of Nishlik Lake.[4] Both lakes and the river lie within Wood-Tikchik State Park,[4] at 1.6 million acres (6,500 km2) the largest state park in the United States.[5]
Alaska Fishing says the river "makes an exciting float...with some potentially good fishing...".[6] Boating dangers include overhanging vegetation and bears, which feed on salmon. The main game fish frequenting the Tikchik are Arctic grayling, char, and red salmon, as well as lake trout in the lakes.[6]