The Cowboys was conceived as an hour-long series, but ABC decided to reduce the running time to a half-hour format. The format change did not lead to increased viewers, and the show was the victim of early cancellation. As a traditional television Western, it was an aberration compared to most television trends of the 1970s (as most had ended production several years prior, and only Gunsmoke was still in production by then).
Guest stars included Cal Bellini as Wa-Cha-Ka in "The Indian Givers", Kevin Hagen as Josh Redding in "Death on a Fast Horse", and Lurene Tuttle as Grandma Jesse in "Many a Good Horse Died".