Sultanum Begum (Persian: سلطانم بیگم; (c. 1516 – 1593), also known as Kadam Ali Soltan Khanum,^[1] was the first wife and chief consort^[2] of the second Safavid king Tahmasp I. She was the mother of her husband's successor, Ismail II, and the mother of Mohammad Khodabanda, who reigned from 1578 until his overthrow in 1587.

Sultanum Begum was the daughter of Isa Beg Mawsillu of the Aq Quyunlu.^[1] Like Tahmasp's mother Tajlu Khanum, Sultanum belonged to the Turcoman Mawsillu tribe and was a maternal third cousin of her husband.^[3] Musa Soltan, governor of Azerbaijan was his brother. Begum had two children during her marriage.^[2]

Sultanum Begum rose to become the leader of the safavid harem after Tajlu Khanum's exile to Shiraz in 1540. She had an independent royal court and her vizier was Khwaja Ibrahim Khalil. She also gained the honorific title of Mahd-i Ulya.^[2]

She mainted her strong position during the reign of Ismail II as her tribe, Mawsillu, also supported him. She was alive during her son Mohammad Khodabanda's and grandson Abbas I's reigns.