The congregation dwindled due to the construction of nearby interstate highways, and the Roman Catholic Diocese of Cleveland closed the church in 1986. It was later deconsecrated.[2] The friary and school suffered moderate damage on January 25, 1993, after a fire set by homeless people who sought shelter in the building got out of control. A second, much more severe fire (whether set by homeless individuals or vandals was unclear) occurred inside the church itself on February 15, 1993.[3] A third fire on February 19, 1993, destroyed the remainder of the structure. The church was demolished on February 20.[4]
Prior to the fires, the stained glass windows, artwork, and most of the other useful items at St. Joseph's Church and Friary had been removed and given to other Catholic Churches for use.[5]