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South Carolina Highway 340
Route information
Maintained by SCDOT
Length	10.990 mi[1] (17.687 km)
Major junctions
South end	SC 403 near Timmonsville
Major intersections	I-20 near Florence US 52 in Darlington
North end	SC 34 / SC 151 in Darlington
Location
Country	United States
State	South Carolina
Counties	Darlington
Highway system
South Carolina State Highway System Interstate US State Scenic
← SC 336 → SC 341

South Carolina Highway 340 (SC 340) is a 10.990-mile-long (17.687 km) state highway in the U.S. state of South Carolina. The highway connects the Timmonsville area with Darlington.

SC 340 begins at an intersection with SC 403 (Oates Highway) north-northwest of Timmonsville, within Darlington County. It travels to the northeast and crosses Middle Swamp and Myrtle Branch before an interchange with Interchange 20 (I-20). It crosses over Jeffries Creek and High Hill Creek before entering the city limits of Darlington. There, it intersects U.S. Route 52 (US 52; Governor Williams Highway). It crosses some railroad tracks before it meets its northern terminus, an intersection with SC 34 (Pearl Street).^[2]

The entire route is in Darlington County.

Location	mi[1]	km	Destinations	Notes
​	0.000	0.000	SC 403 (Oates Highway) – Timmonsville, Hartsville	Southern terminus
​	3.940	6.341	I-20 – Columbia, Florence	I-20 exit 137
Darlington	10.240	16.480	US 52 (Governor Williams Highway) to SC 34 – Bennettsville, Cheraw, Florence
	10.990	17.687	SC 34 (Pearl Street / SC 151) – Bishopville, Dillon	Northern terminus
1.000 mi = 1.609 km; 1.000 km = 0.621 mi

• U.S. roads portal
• United States portal

• Media related to South Carolina Highway 340 at Wikimedia Commons
• SC 340 South Carolina Hwy Index