In July 2019, Jakobsson joined Real Madrid Feminino of the Spanish Primera División, who at that time went under the name CD Tacon, along with her national teammate, Kosovare Asllani.[14] During her first season in Spain, Jakobsson scored most goals and most assists in the capital club scoring eight goals and seven assists.[15]
In June 2021, Jakobsson announced that she was departing Real Madrid.[16] On 2 July 2021, she signed with Bayern Munich in the top German league, the Frauen-Bundesliga.[17] Jakobsson made only five appearances with Bayern Munich, and in January 2022, was signed by the American team San Diego Wave FC of the National Women's Soccer League.[18]
On 11 September 2024, Jakobsson and the San Diego Wave agreed to a mutual contract termination.[19] Jakobsson had played in 52 matches and made 30 starts in her tenure with the Californian club.[20] Two days after the announcement of her departure from the Wave, Jakobsson signed with Women's Championship club London City Lionesses on a two-year contract.[21]
In the Quarter-Final of the 2019 FIFA Women's World Cup, Jakobsson scored a game-tying goal within ten minutes of Germany taking an early lead. Sweden would go on to win the match, posting their first victory over the Germans in a major tournament since the 1995 World Cup.[24][25] She also tallied what proved to be the winning goal in the 3rd Place Match of that tournament, scoring in the 22nd minute against England.[26]
Jakobsson was voted as the player of the match in the Quarter-Final vs Germany, and the 3rd Place Match against England.