The siege of Nisibis took place when the Sasanians under Shah Shapur I besieged the Roman city of Nisibis in 252. This marks the beginning of Shapur's I second invasion of the Roman empire which saw the first Sassanid invasion of Syria; the year of the invasion is debated as Shapur's inscription from Naqsh-e Rustam regarding his second campaign against Rome do not mention the city of Nisibis. But Syriac and Arabic sources, mainly the Chronicle of Seert and Al-Tabari, mention that Shapur took Nisibis in his eleventh regnal year; according to the historian David Stone Potter, this regnal year is 252. Another Syriac account, the Liber Caliphorum, from the eighth century, mentions the invasion of the city in 252.[3][4]
^Empress Zenobia: Palmyra's Rebel Queen "Shapur also claimed that he had devastated Syria and captured thirty-seven cities with their surrounding territories. He may have captured Nisibis, and destroyed Antioch."
Edwell, Peter (2007). Between Rome and Persia: The Middle Euphrates, Mesopotamia and Palmyra Under Roman Control. Routledge. ISBN978-1-134-09573-5.
Dodgeon, Michael H; Lieu, Samuel N. C (2002). The Roman Eastern Frontier and the Persian Wars AD 226-363: A Documentary History. Routledge. ISBN978-1-134-96113-9.
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