In 1994 she was the women's leader in Santa Cruz of the Bartolina Sisa Confederation[1] and she became the conferation's executive.[2] In 2019 she was invited to the United Nations to celebrate International Mother Earth Day as a representative of the Bartolina Sisa confederation.[3]
In 2020 "her" President Evo Morales was involved in choosing a new Governor of Santa Cruz. He endorsed the former Mayor of Warnes, Mario Cronenbold, but he withdrew his support when Cronenbold made statements in favor of not prosecuting an anti-Morales activist.[4] Someone threw a plastic chair at Morales in what became known as the "silletazo."[5]
The "silletazo" was met by various reactions. Flores supported Morales noting that he "deserves respect" and people "cannot be bouncing around with chairs." However, she also pointed out candidates should not be chosen by the pointing of a finger.[2]
In 2024 she was Bolivia's ambassador to Ecuador when the Ecuadorian government raided the Mexican embassy to retrieve an ex-vice president, Jorge Glas, who was avoiding justice. Flores was summoned by Bolivia in response to the invasion of an embassy.[6]