San Sebastián Río Hondo
Municipality and town
San Sebastián Río Hondo Location in Mexico
Coordinates: 16°10′N 96°27′W / 16.167°N 96.450°W / 16.167; -96.450
Country	Mexico
State	Oaxaca
Time zone	UTC-6 (Central Standard Time)
• Summer (DST)	UTC-5 (Central Daylight Time)

San Sebastián Río Hondo is a town and municipality in Oaxaca in south-western Mexico. The municipality covers an area of km². It is part of the Miahuatlán District in the south of the Sierra Sur Region.

As of 2005, the municipality had a total population of .^[1]