On January 26, 2019, Okuayinonu committed to the Maryland Football. At Maryland, Okuayinonu had a total of 90 tackles, 12.0 tackles for loss and 5.5 sacks.[2] After the 2021 Pinstripe Bowl, Okuayinonu declared for the draft.[1]
Okuayinonu was not selected in the 2022 NFL draft. On April 30, 2022, he signed with the Tennessee Titans as an undrafted free agent.[4] He was waived on August 30, 2022 and signed to the practice squad the next day.[5][6] He was promoted to the active roster on October 4.[7] The Titans waived Okuayinonu on December 6, 2022 and re-signed with the practice squad.[8] He was promoted to the active roster on December 29, then waived the next day and re-signed back to the practice squad.[9][10]
Okuayinonu signed a reserve/future contract on January 10, 2023.[11] On August 29, 2023, he was waived for final roster cuts before the start of the 2023 season.[12] Though Okuayinonu signed with the practice squad on August 30, the next day he was released again.[13][14]
San Francisco 49ers
On January 10, 2024, Okuayinonu was signed to the San Francisco 49ers practice squad.[15] He signed a reserve/future contract on February 13, 2024.[16]
Okuayinonu was waived by the 49ers on August 28, 2024, and re-signed to the practice squad.[17][18] He was promoted to the active roster on September 28.[19]