Saffarin, like all of Palestine was incorporated into the Ottoman Empire in 1517. In the 1596 tax registers, part of the nahiya ("subdistrict") of Jabal Sami, part of the larger Sanjak of Nablus. It had a population of 8 households, all Muslims. The inhabitants paid a fixed tax rate of 33.3% on agricultural products, including wheat, barley, summer crops, olive trees, goats and beehives, in addition to occasional revenues and a press for olive oil or grape syrup, and a fixed tax for people of Nablus area; a total of 9,167 akçe. 3/24 of the revenue went to the WaqfHalil ar-Rahman.[10]
During the 18th century, a group of TransjordanianHuwaytat Arabs, settled in the village. The newcomers formed several families, including the Dar Hasan hamula, cmprised of the Hannun, Salih, Abu Dhiyab, ‘Ali Abu Bakr, and Samara families. In the middle of the 19th century, the Hannun and Samara families moved to Tulkarm together with other families of Saffarin. Later on, members of the Hannun family established the plantation/village of Bayyarat Hannun near the coastal city of Netanya, and would serve as mayors of Tulkarm for most of the 20th century.[11]
Around the turn of the 20th century, Saffarin was one of the villages in which the Hannun family owned extensive estates. The Hannuns fostered close ties with the clans inhabiting the village.[15]
In the 1945 statistics the population of Saffarin was 530 Muslims,[18] with 9,687 dunams of land according to an official land and population survey.[19] Of this, 1,624 dunams were used plantations and irrigable land, 1,384 for cereals,[20] while 13 dunams were built-up (urban) land.[21]
^Millard, Alan (1995-11-01). "The Knowledge of Writing in Iron Age Palestine". Tyndale Bulletin. 46 (2): 208. doi:10.53751/001c.30407. ISSN2752-7042. Sixteen of the twenty-seven place names can be identified with those of Arab villages existing in the past hundred years in the countryside around Samaria (such as Elmatan, 28.3, modern Ammatin, or Sepher, 16a, b.1, 2, 29.3, modern Saffarin)