Locsin was launched to stardom in Regal Films' Disgrasyada (1978) which became a huge box-office hit. Since then, she was given roles which are sexy like Menor de Edad (1979), Love Affair (1979), Ina, Kapatid, Anak (1979), Rissa Jones (1979), Stepsisters (1979), Waikiki (1980), Disco Madhouse (1980), Manila by Night (1980), Unang Yakap (1980), Kambal sa Uma (1980), Kasalanan Ba (1981), among others.
She also had the privilege of transforming to Darna via the low-budgeted, poorly-directed Bira, Darna, Bira (1979) with Romnick Sarmenta as Ding.[2] In 1982, she essayed the role of a ghost in Haplos (1982) playing support to Vilma Santos. Other memorable roles were in movies, Salawahan (1979), Working Girls (1984), Soltero (1984), Kailan Tama ang Mali? (1985), Kapag Puso ang Sinugatan (1985) and Huwag Mo kaming Isumpa (1985).
In 1981 to 1982, she top-billed an afternoon drama show over GMA-7 entitled, Hiyas.
As a commercial model, she endorsed, "San-ing" and "Lyna" medicated products, including Bax jeans during the late 70s until early 80s.
As a film actress she has starred in lead roles through the 70s 80s and 90s in the late 90s she starred in Daytime dramas such as Kadenang Kristal and Mula sa Puso between 1995 and 1999 and in 1999 was tapped to portray Katrina in Marinella, replacing Hilda Koronel as the main antagonist of the series. She ventured in many Primetime Television dramas and in 2006, she starred in more Television dramas memorably as Edad in Gulong Ng Palad remake on ABS-CBN and 2007 she starred as a antiheroine in Pangarap Na Bituin in 2007 she starred in the hit tv series Margarita as she ventured away she did more roles then ever. Her public marriage to actor Al Tantay dissolved.
Personal life
She married Al Tantay, but they separated after a few years. She remarried to a former basketball player turned Evangelical Christian pastor, Padim Israel. She has three daughters.
^"31st FAMAS Awards (1983)". The Filipino Academy of Movie Arts and Sciences. July 17, 2006. Archived from the original on July 17, 2006. Retrieved March 15, 2024.
^"35th FAMAS Awards". The Filipino Academy of Movie Arts and Sciences. July 17, 2006. Archived from the original on July 17, 2006. Retrieved March 15, 2024.