Pyruvate oxidase

pyruvate oxidase
Identifiers
EC no.1.2.3.3
CAS no.9001-96-1
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO
Search
PMCarticles
PubMedarticles
NCBIproteins

In enzymology, a pyruvate oxidase (EC 1.2.3.3) is an enzyme that catalyzes the chemical reaction

pyruvate + phosphate + O2 acetyl phosphate + CO2 + H2O2

The 3 substrates of this enzyme are pyruvate, phosphate, and O2, whereas its 3 products are acetyl phosphate, CO2, and H2O2.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the aldehyde or oxo group of donor with oxygen as acceptor. The systematic name of this enzyme class is pyruvate:oxygen 2-oxidoreductase (phosphorylating). Other names in common use include pyruvic oxidase, and phosphate-dependent pyruvate oxidase. This enzyme participates in pyruvate metabolism. It has 2 cofactors: FAD, and Thiamin diphosphate.

Structural studies

As of late 2007, 12 structures have been solved for this class of enzymes, with PDB accession codes 1POW, 1POX, 1V5E, 1V5F, 1V5G, 1Y9D, 2DJI, 2EZ4, 2EZ8, 2EZ9, 2EZT, and 2EZU.

References

  • Williams FR, Hager LP (1966). "Crystalline flavin pyruvate oxidase from Escherichia coli. I Isolation and properties of the flavoprotein". Arch. Biochem. Biophys. 116 (1): 168–76. doi:10.1016/0003-9861(66)90025-7. PMID 5336022.
  • Tittmann K, Wille G, Golbik R, Weidner A, Ghisla S, Hubner G (2005). "Radical phosphate transfer mechanism for the thiamin diphosphate- and FAD-dependent pyruvate oxidase from Lactobacillus plantarum Kinetic coupling of intercofactor electron transfer with phosphate transfer to acetyl-thiamin diphosphate via a transient FAD semiquinone/hydroxyethyl-ThDP radical pair". Biochemistry. 44 (40): 13291–303. doi:10.1021/bi051058z. PMID 16201755.


This EC 1.2 enzyme-related article is a stub. You can help Wikipedia by expanding it.

Read other articles:

Consiglio di mutua assistenza economica

Consiglio di mutua assistenza economica Fondazione18 gennaio 1949 Scioglimento28 giugno 1991 Scopopolitico, economico, progresso scientifico e tecnologico Sede centrale Mosca Lingua ufficialeRusso (durante i lavori, altrimenti lingue ufficiali degli Stati membri)[1] Membri Unione Sovietica Germania Est (Fino al 1990) Cecoslovacchia Albania (Fino al 1987) Polonia Ungheria Bulgaria Romania Cuba Vietnam MongoliaMembro associato: ...

 

Ernst Rüdiger von Starhemberg

Ernst Rüdiger von StarhembergLahir(1638-01-12)12 Januari 1638Graz, Kadipaten SteiermarkMeninggal4 Januari 1701(1701-01-04) (umur 62)Vösendorf, Kadipaten Utama AustriaDikebumikanWinaPengabdian Kekaisaran Romawi SuciDinas/cabangAngkatan Darat KekaisaranLama dinas1660–1701PangkatGeneralfeldmarschallPerang/pertempuranPerang Turki Besar Pertempuran Wina Pengepungan Buda Graf Ernst Rüdiger von Starhemberg (12 Januari 1638 – 4 Januari 1701) menjabat sebagai gubern...

 

Géophysique

Pour les articles homonymes, voir Géophysique (homonymie). GéophysiqueCarte du séisme de 2010 en Haïti.Partie de Physique, géologiePratiqué par Géophysicien ou géophysicienne (d)Objets Terreprocessus géologique (d)magmatisme (en)modifier - modifier le code - modifier Wikidata La géophysique est l'étude des caractéristiques physiques de la Terre, ou d'autres planètes, utilisant des techniques de mesures indirectes (gravimétrie, géomagnétisme, sismologie, radar géologique, ré...

Piala Raja Spanyol 1910

Piala Raja Spanyol 1910 adalah edisi ke-8 dari penyelenggaraan Piala Raja Spanyol, turnamen sepak bola di Spanyol dengan sistem piala. Karena adanya beberapa hal yang tidak disepakati antara juara bertahan Club Ciclista de San Sebastián dan beberapa tim peserta lainnya, maka terjadi dualisme kompetisi, yakni yang diselenggarakan oleh Federasi Sepak Bola Spanyol (Real Federación Española de Fútbol, RFEF) dan oleh Unión Española de Clubes de Fútbol (UECF). RFEF kemudian mengakui kedua pe...

 

Pemilu Amerika Serikat 1790 dan 1791

Artikel ini sebatang kara, artinya tidak ada artikel lain yang memiliki pranala balik ke halaman ini.Bantulah menambah pranala ke artikel ini dari artikel yang berhubungan atau coba peralatan pencari pranala.Tag ini diberikan pada Januari 2023. Pemilu Amerika Serikat 1790-17911788 / 17891792 / 1793Tanggal bervariasi tergantung negara bagian9 dari 26 kursi di Senat Amerika Serikat, ditambah pemilu khusus14 kursi untuk meraih status mayoritasKandidat   Partai mayoritas Partai minoritas ...

 

Синелобый амазон

Синелобый амазон Научная классификация Домен:ЭукариотыЦарство:ЖивотныеПодцарство:ЭуметазоиБез ранга:Двусторонне-симметричныеБез ранга:ВторичноротыеТип:ХордовыеПодтип:ПозвоночныеИнфратип:ЧелюстноротыеНадкласс:ЧетвероногиеКлада:АмниотыКлада:ЗавропсидыКласс:Пт�...

John Klingberg

Swedish ice hockey player (born 1992) Ice hockey player John Klingberg Klingberg with the Dallas Stars in 2022Born (1992-08-14) 14 August 1992 (age 31)Gothenburg, SwedenHeight 6 ft 3 in (191 cm)Weight 190 lb (86 kg; 13 st 8 lb)Position DefenceShoots RightNHL teamFormer teams Toronto Maple LeafsFrölunda HCJokeritSkellefteå AIKDallas StarsAnaheim DucksMinnesota WildNational team  SwedenNHL Draft 131st overall, 2010Dallas StarsPlaying career 2010...

 

Sindiran Perdagangan

Ostrakon abad ke-19 yang terinskripsi dengan bagian dari Sindiran Perdagangan. Torino, Museo Egizio Sindiran Perdagangan, juga disebut Instruksi Dua-Kheti, adalah sebuah karya sastra Mesir kuno didaktik.[1] Karya tersebut mengambil bentuk sebuah Instruksi, yang terdiri dari sebuah naskah dari Sile yang bernama Dua-Kheti kepada putranya Pepi. Pengarangnya dianggap oleh beberapa orang juga mengkomposisikan Instruksi Amenemhat.[2] Penggunaan dalam Ben Sira Kisah Mesir tersebut di...

 

Anne Desclos

French journalist and novelist (1907–1998) This article needs additional citations for verification. Please help improve this article by adding citations to reliable sources. Unsourced material may be challenged and removed.Find sources: Anne Desclos – news · newspapers · books · scholar · JSTOR (July 2022) (Learn how and when to remove this message) Anne DesclosBorn(1907-09-23)23 September 1907Rochefort, FranceDied27 April 1998(1998-04-27) (aged...

Шаблон:Мифология

МифологияРитуально-мифологическийкомплекс Система ценностей Сакральное Миф Мономиф Теория основного мифа Ритуал Обряд Праздник Жречество Мифологическое сознание Магическое мышление Низшая мифология Модель мира Цикличность Сотворение мира Мировое яйцо Мифическое �...

 

拉吉夫·甘地

拉吉夫·甘地राजीव गांधीRajiv Gandhi1987年10月21日，拉吉夫·甘地在阿姆斯特丹斯希普霍尔机场 第6任印度总理任期1984年10月31日—1989年12月2日总统吉亞尼·宰爾·辛格拉马斯瓦米·文卡塔拉曼前任英迪拉·甘地继任維什瓦納特·普拉塔普·辛格印度對外事務部部長任期1987年7月25日—1988年6月25日前任Narayan Dutt Tiwari（英语：Narayan Dutt Tiwari）继任納拉辛哈·拉奥任期1984年10�...

 

Total Divas

American reality television series Total DivasGenreReality televisionStarring Brie Bella Cameron Eva Marie JoJo Naomi Natalya Nikki Bella Summer Rae Rosa Mendes Alicia Fox Paige Mandy Rose Lana Maryse Renee Young Alexa Bliss Carmella Nia Jax Ronda Rousey Sonya Deville Opening themeTop of the World by CFO$Country of originUnited StatesOriginal languageEnglishNo. of seasons9No. of episodes120 (list of episodes)ProductionExecutive producers Gil Goldshein Jeff Jenkins Mary-Ellis Bunim Jonathan Mu...

Stability theory

Part of mathematics that addresses the stability of solutions For the branch of model theory, see stable theory. Stability diagram classifying Poincaré maps of linear autonomous system x ′ = A x , {\displaystyle x'=Ax,} as stable or unstable according to their features. Stability generally increases to the left of the diagram.[1] Some sink, source or node are equilibrium points. In mathematics, stability theory addresses the stability of solutions of differential equations and...

 

Pallone d'oro 1983

L’edizione 1983 del Pallone d'oro, 28ª edizione del premio calcistico istituito dalla rivista francese France Football, fu vinta dal francese Michel Platini (Juventus). I giurati che votarono furono 26, provenienti da Austria, Belgio, Bulgaria, Cecoslovacchia, Danimarca, Finlandia, Francia, Germania Est, Germania Ovest, Grecia, Inghilterra, Irlanda, Italia, Jugoslavia, Lussemburgo, Paesi Bassi, Polonia, Portogallo, Romania, Scozia, Spagna, Svezia, Svizzera, Turchia, Ungheria e Unione Sovie...

 

2000 Summer Olympics

Multi-sport event in Sydney, Australia Sydney 2000 redirects here. For the Summer Paralympics, see 2000 Summer Paralympics. For the video game, see Sydney 2000 (video game). Games of the XXVII OlympiadEmblem of the 2000 Summer Olympics[a]Host citySydney, AustraliaMottoShare the Spirit – Dare to Dream (bid), The Games of the New Millennium (during the games)Nations199Athletes10,647 (6,579 men, 4,068 women)[1]Events300 in 28 sports (40 disciplines)Opening15 September 2000Closi...

Turner Layton

American singer-songwriter and pianist (1894–1978) Turner LaytonTurner Layton (left) and his musical partner Clarence Johnstone in 1933Background informationBirth nameJohn Turner Layton, Jr.Born(1894-07-02)2 July 1894Washington, D.C., United StatesDied6 February 1978(1978-02-06) (aged 83)London, EnglandGenresJazz, vocalOccupation(s)SingerYears active1918–1946Musical artist Sheet music cover for a patriotic Creamer & Layton song, 1918 Turner Layton (July 2, 1894 – February 6, 19...

 

Criptoportico

Il criptoportico dell'imperatore Nerone al Palatino (Roma). Un criptoportico (dal greco criptos (nascosto) e dal latino porticus), nell'architettura dell'antica Roma, era un corridoio o una via di passaggio coperta. Il criptoportico può essere al livello del terreno, ma di solito è seminterrato, e supportava una struttura come un foro o una villa romana, nel quale caso fungeva da basis villae, come corridoio di servizio non esposto alla vista. È spesso ricoperto a volta e presenta delle ap...

 

Engine block

Part of an internal combustion engine This article needs additional citations for verification. Please help improve this article by adding citations to reliable sources. Unsourced material may be challenged and removed.Find sources: Engine block – news · newspapers · books · scholar · JSTOR (March 2022) (Learn how and when to remove this message) Block of a modern V6 diesel engine. The large holes are the cylinders, the small round orifices are mountin...

El Paraíso, El Paraíso

For other uses, see El Paraíso. Municipality in El Paraíso, HondurasEl ParaísoMunicipalityEl ParaísoLocation in HondurasCoordinates: 13°52′N 86°33′W / 13.867°N 86.550°W / 13.867; -86.550CountryHondurasDepartmentEl ParaísoArea • Municipality356 km2 (137 sq mi)Population (2023 projection)[1] • Municipality47,542 • Density130/km2 (350/sq mi) • Urban31,649 El Paraíso (Spanish pro...

 

Franklin Park Conservatory

Botanical garden in Columbus, Ohio Franklin Park Conservatory and Botanical GardensConservatory greenhouses and groundsEstablished1895; modern entity in 1992Location1777 E. Broad St., Columbus, OhioCoordinates39°57′57″N 82°57′10″W / 39.965859°N 82.952890°W / 39.965859; -82.952890Visitors353,399 (2018)[1]President and CEOBruce HarkeyChairpersonPatrick HenthorneArchitectJohn M. Freese (original)Böhm-NBBJ (expansion)Public transit access 10 CoGoNeares...