Prunskienė Cabinet was the 1st cabinet of Lithuania since the declaration of independence in 1990. It consisted of the Prime Minister and 17 government ministers.^[1]

Kazimiera Prunskienė was appointed as the first Prime Minister by the Supreme Council of Lithuania on 17 March 1990, six days after declararing the independence. During the next year, the government worked on securing the Lithuanian independence, rather than introducing substantial reforms. Economic crisis and rising prices led to dissatisfaction with the government and its dismissal on 10 January 1991, in the opening stages of the January events.^[2]

It was the only government in history of independent Lithuania to have two deputy prime ministers. Also, it was first in history of Lithuania to be led by woman.

The following ministers served on the Prunskienė Cabinet.^[1]