On 25 January 1699 she married Philip William, Margrave of Brandenburg-Schwedt (1669–1711), in Oranienbaum. Although the couple had their own palace in Berlin, they lived mostly in Schwedt. After the death of her husband, Johanna Charlotte went back to Berlin and looked after the education of her children.
In 1729, she had herself elected abbess of Herford Abbey, which stood under Prussian protection. She was sworn in as the new abbess on 10 October 1729, but lived at first in Buchholz, Schaumburg. It was not until 1735 that she took up permanent residence in Herford. Later in 1729, she added a secular order to her abbey[1] and accepted 17 canonesses. She appointed Hedwig Sophie of Schleswig-Holstein-Gottorp as her coadjutor. Hedwig Sophie later became her successor.
Johanna Charlotte died of an "apoplexy", without being ill, in the night of 30 to 31 March 1750. She was buried in the crypt of the Collegiate Chapel of Herford, which had just been renovated.
Issue
From their marriage, Charlotte Johanna had the following children:
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