Point Breeze has six borders, five with the Pittsburgh neighborhoods of North Point Breeze to the north, Regent Square to the southeast, Squirrel Hill South to the south and southwest, Squirrel Hill North to the west, and Shadyside to the northwest. The other border is with the borough of Wilkinsburg to the east. Point Breeze also runs catty-corner (without a direct border) with the Pittsburgh neighborhood of Larimer to the north at the intersection of Penn and Fifth Avenues (This intersection also serves as an east–west "diagonal" for the Pittsburgh neighborhoods of Shadyside and North Point Breeze).
Malcolm James McCormick (January 19, 1992 – September 7, 2018), known professionally as Mac Miller.
David McCullough (July 7, 1933 – August 7, 2022), noted historian and author, two-time winner of the Pulitzer Prize, was born and raised in Point Breeze.[6]