He briefly returned to Super League with Wigan Warriors in 2006. In 2022, Wilkes admitted that he had taken performance-enhancing drugs at his previous club, Whitehaven, prior to his to move to Wigan.[5]
Widnes Vikings
His next move was to the Widnes Vikings. He played for Widnes Vikings in the 2006 National League Grand Final. After the season, he required reconstructive shoulder surgery.[6] In 2007, he scored 15 tries in 34 games with Widnes Vikings before returning to Super League with Wakefield Trinity Wildcats the following year.[7]
Wakefield Trinity Wildcats
He returned to the Super League with Wakefield Trinity Wildcatsin 2007.[7]
Wilkes was a consistent feature within the 2009 Wakefield Trinity Wildcats squad, and they managed to secure a fifth-place finish within the Super League reaching the play-offs.
Harlequins Rugby League
He then moved to Harlequins RL, spending two years there before returning to Wakefield Trinity Wildcats.[citation needed]
Wakefield Trinity Wildcats
Wilkes rejoined Wakefield Trinity Wildcats in 2012.
Leigh
Wilkes left Wakefield Trinity Wildcats to rejoin Leigh in 2014, captained the side Leigh to the League Leaders' Shield, and the Championship Grand Final victory. At the end of the 2015 season, he announced he was leaving Leigh to sign for his hometown club Barrow.[citation needed]
Barrow Raiders
Wilkes left the Barrow Raiders after spending the 2016 and 2017 seasons at the League 1 club.
Workington Town
Wilkes joined Workington Town ahead of the 2018 season.
He was named club captain for the 2018 season, he played for town for 2 years making 43 appearances and scoring 18 tries, Wilkes announced his retirement in August 2019.[8]
International career
He was named to the Scotland training squad for the 2008 Rugby League World Cup[9] and was named to the full Scotland squad for the 2008 Rugby League World Cup. He scored the winning try over Fiji in Scotland's first ever World Cup win.[10] Wilkes was recalled to the Scotland squad in 2018, at the age of 38, for the European championships.