Obtusifoliol

Obtusifoliol
Identifiers
3D model (JSmol)
ChEBI
ChEMBL
ChemSpider
KEGG
UNII
  • InChI=1S/C30H50O/c1-19(2)20(3)9-10-21(4)23-13-17-30(8)26-12-11-24-22(5)27(31)15-16-28(24,6)25(26)14-18-29(23,30)7/h19,21-24,27,31H,3,9-18H2,1-2,4-8H3/t21-,22+,23-,24?,27+,28+,29-,30+/m1/s1
    Key: MMNYKQIDRZNIKT-YLANKJTKSA-N
  • InChI=1S/C30H50O/c1-19(2)20(3)9-10-21(4)23-13-17-30(8)26-12-11-24-22(5)27(31)15-16-28(24,6)25(26)14-18-29(23,30)7/h19,21-24,27,31H,3,9-18H2,1-2,4-8H3/t21-,22+,23-,24?,27+,28+,29-,30+/m1/s1
    Key: MMNYKQIDRZNIKT-YLANKJTKSA-N
  • C[C@@H]1[C@H](CC[C@]2(C1CCC3=C2CC[C@]4([C@]3(CC[C@@H]4[C@H](C)CCC(=C)C(C)C)C)C)C)O
Properties
C30H50O
Molar mass 426.729 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

Obtusifoliol is a metabolic intermediate of sterols made by certain fungi. It can be converted to delta8,14-sterol by the enzyme ERG11 (CYP51F1).[1]

References

  1. ^ Park, HG; Lee, IS; Chun, YJ; Yun, CH; Johnston, JB; Montellano, PR; Kim, D (1 May 2011). "Heterologous expression and characterization of the sterol 14α-demethylase CYP51F1 from Candida albicans". Archives of Biochemistry and Biophysics. 509 (1): 9–15. doi:10.1016/j.abb.2011.02.002. PMC 3079055. PMID 21315684.


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